Protein Alignment osy and abca2

DIOPT Version :10

• Sequence 1: NP_001034071.1
• Gene: osy / 43186
• FlyBaseID: FBgn0053970
• Length: 777
• Species: Drosophila melanogaster
• Sequence 2: XP_005165287.2
• Gene: abca2 / 100006090
• ZFINID: ZDB-GENE-050517-1
• Length: 2503
• Species: Danio rerio
• Alignment Length: 1018
• Identity: 204/1018 - (20%)
• Similarity: 351/1018 - (34%)
• Gaps: 351/1018 - (34%)

  Fly    48 VCVRRAHKMYGSSKNPNVVLDGLNMTVPKGSIYGLLGASGCGKTTLLSCIVGRRRLNSGEIWVLG 112
            ||:.:..|:|.:..  .:.|:.|::.:.:..:...||.:|.||||.:|.:.|.....||...:.|
Zfish  1041 VCIDKLTKVYKTGS--KLALNKLSLNLHENQVVSFLGHNGAGKTTTMSILTGLFPPTSGSATIYG 1103

  Fly   113 GRPGSRGSGVPGPRIGYMPQEIALYGEFTMRETLIYFGIISAMSKGDIEDRTEFLLKLLNLPN-A 176
            ....:....: ...:|..||...|:.:.::.|.|.::..:..|::.||....:.:::.|.|.| .
Zfish  1104 HDIRTEMERI-RQNLGMCPQHNVLFDKLSVEEHLWFYSRLKGMAEEDIRKEMDKMIEDLELSNKR 1167

  Fly   177 SKFVKNLSGGQQRRVSLAVALLHEPELLILDEPTVGVDPVLRQSIWDHLVDITKNGHTTVIITTH 241
            ...|:.||||.:|::|:|:|.:.....:||||||.||||..|::||| |:...|.|. |::::||
Zfish  1168 HSLVQTLSGGMKRKLSVAIAFVGGSRAVILDEPTAGVDPYARRAIWD-LILKYKQGR-TILLSTH 1230

  Fly   242 YIDECAQAHMIG----LLRGGKMLAEESPDYLRQQY----------------NAD---------- 276
            ::||   |.::|    ::..||:....||.:|:..|                .||
Zfish  1231 HMDE---ADLLGDRIAIISHGKLKCCGSPLFLKSTYGDGYKLTLVKKQSDSHTADQSSQSPSSSI 1292

  Fly   277 ----------------------------------------------------------------- 276
                                                                             
Zfish  1293 SPCSENRVTQFIRQYVASCLLVSDSNTELSYVLPSEAVKKGCFERLFQALEQSLDSLALTSFGVM 1357

  Fly   277 --SLEDVFLKLS----VLQNMGKRRRSS------------IAQEIVEQVTVPAISNPALDMSDEQ 323
              :||:||||:|    .|:|.....:.|            :.....|.....|:..|.:::|:..
Zfish  1358 DTTLEEVFLKVSEEDLSLENSDADMKDSPGGASAGKPSGLLGGPQCEGAPAAAVMRPEVELSNLM 1422

  Fly   324 HAAEIS----------------GE--------FGDNISM--------SSAARDPISTTAPAAPPL 356
            ..:.:|                |:        :||...:        |::.||..|:      |.
Zfish  1423 MCSRLSPSQASLQSGSSLGSVRGDEGGPYSEFYGDYCPLFDNGQDLDSASLRDEESS------PQ 1481

  Fly   357 PPPQEIPTSF----WYNLHVMQSHHLHALIWKNFLWMMRNV-GVM-------LFI-----VGLPV 404
            |...|...||    |:    ::....|.||.|.|....||. |:.       .|:     |.|.|
Zfish  1482 PTVLEGQGSFKLDGWW----LKLRQFHGLIVKRFHCAKRNTKGIFSQILLPAFFVCVAMTVALSV 1542

  Fly   405 VQI-----LLFCYAIGHD---PTGLKLAVANHEMS-----------GEMIMEQF---------CP 441
            .:|     |:...:..|:   |.|..:..||.:.|           .:.|:...         |.
Zfish  1543 PEIGDLPPLILSPSQYHNYTQPRGNFIPYANEDRSQYRTKFSPDAGPQRIVNTLRLPSGVGATCI 1607

  Fly   442 VHTGCNQTMLSCRYLDMLVK--------NKSMVVQYVTDDEMAYEEVRKGRAWAALVIQP----- 493
            :.|..|.|      ||.|.:        :|::..:|.  |.|..:...:|...:..|..|
Zfish  1608 LKTPFNST------LDQLAQTLNPYANNSKTLAARYF--DSMCLDSFTQGVPLSNFVPPPPSPAP 1664

  Fly   494 -------------NYTA-----------------SLMERVE-------DGRYAEDGT-------- 513
                         ||||                 |:.|.|.       .|.....|.
Zfish  1665 SDDPEAHFEDGLWNYTAAPTTVREMATSPPTLPLSIHEPVRCICSMQGTGFSCPSGVGGRPPLMK 1729

  Fly   514 IESSDLAVRMDWSNQQISQ-LLYRDLQYTFFNFVGDMLSDCDVNPKLGRVPVDFQHPVYGYRNPN 577
            :.:.|:.|  |.:.:.:|: |||...:.....:.|..:.:...:     ||..|     |.:.|
Zfish  1730 VVTGDILV--DITGRNVSEYLLYTSDRLRLHRYGGFTVGNIQKS-----VPASF-----GRKTP- 1781

  Fly   578 FTDFAAPGVILTIIFFLAVAVTSGAMLIDRNEGMLERCLVAGITGPEILLSQV-----------V 631
                  |.|       ..:||...:.::..|:|.........:....||.:.:           :
Zfish  1782 ------PMV-------RKIAVRRSSQVLYNNKGYHSMPTYLNVLNNAILRANLPSSKGNPSAYGI 1833

  Fly   632 TQFTVMLSQTTFVLIVSFYFFELTLVGNIWLVVALCILNGLCGMSF---GFVISCAVDTERTATY 693
            |.....:::|:..|.:.:......:|..|:::||         |||   .||:....:....|.:
Zfish  1834 TVTNHPMNRTSASLSLDYLLQGTDVVIAIFIIVA---------MSFVPASFVVFLVAEKSTKAKH 1889

  Fly   694 VAMGSFL-PIV-MLCGIIWP-IEGMFP----LLQFFTAFLP-LTKPTE---SMRSILQRGWGIDN 747
            :...|.. |:. .|...||. :..:.|    :|..|...|| .|.||.   .:...|..||.| .
Zfish  1890 LQFVSGCDPVTYWLANYIWDMLNYLVPATCCVLILFVFDLPAYTSPTNFPAVLSLFLLYGWSI-T 1953

  Fly   748 PVVY--NGFISISSWVLVFLVL------------TILLLKFKK 776
            |::|  :.:..:.|...|||::            |.||..|::
Zfish  1954 PIMYPASFWFEVPSTAYVFLIVINLFIGITATVATFLLQLFER 1996

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
osy	NP_001034071.1	CcmA	50..285	CDD:440746	74/332 (22%)
		YadH	578..773	CDD:440604	47/233 (20%)
abca2	XP_005165287.2	None