Protein Alignment Nil and PTC1

DIOPT Version :10

• Sequence 1: NP_651472.2
• Gene: Nil / 43185
• FlyBaseID: FBgn0039421
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: NP_010278.3
• Gene: PTC1 / 851558
• SGDID: S000002164
• Length: 281
• Species: Saccharomyces cerevisiae
• Alignment Length: 309
• Identity: 100/309 - (32%)
• Similarity: 146/309 - (47%)
• Gaps: 69/309 - (22%)

  Fly     9 LEKPETEKQAQEGHGNGLRYCVSSMQG----WRLEMEDSH----SAACRLKDPFATWSYFAVFDG 65
            ||:|||...        :.|.|...:.    :|..|||.|    :.|.||     .|.|||||||
Yeast     8 LERPETPYD--------ITYRVGVAENKNSKFRRTMEDVHTYVKNFASRL-----DWGYFAVFDG 59

  Fly    66 HAGSQISLHCAEHLMSTILESESFSKHKYEAG--IREGFLQLDEDMRKLYHDQQGGSTAICVF-- 126
            |||.|.|..|.:|| .||:|....:....:..  :.:.||.:||::........|.:.|:||.
Yeast    60 HAGIQASKWCGKHL-HTIIEQNILADETRDVRDVLNDSFLAIDEEINTKLVGNSGCTAAVCVLRW 123

  Fly   127 -----VSPD---------KIYLVNCGDSRAVISRNGAAVISTIDHKPFSPKEQERIQNAGGSVMI 177
                 ||.|         |:|..|.||||.|:.|||.::..|.|||.....|.:|::.|||.:|.
Yeast   124 ELPDSVSDDSMDLAQHQRKLYTANVGDSRIVLFRNGNSIRLTYDHKASDTLEMQRVEQAGGLIMK 188

  Fly   178 KRINGTLAVSRAFGDYDFKNDGSKSPVDQMVSPEPDIIVCNRSEHDEFIVVACDGIWDVMTSSEV 242
            .|:||.|||:|:.||..|         |.:|...|.......:..|:|:::||||:|||:...:.
Yeast   189 SRVNGMLAVTRSLGDKFF---------DSLVVGSPFTTSVEITSEDKFLILACDGLWDVIDDQDA 244

  Fly   243 CEFIR--------SRLLVTYDLPMIVNSVLDICLHKGSRDNMTLLLLLL 283
            ||.|:        :::||.|            .|..|:.||:|::::.|
Yeast   245 CELIKDITEPNEAAKVLVRY------------ALENGTTDNVTVMVVFL 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nil	NP_651472.2	PP2Cc	27..277	CDD:238083	93/283 (33%)
		PP2C_C	284..355	CDD:429684	100/309 (32%)
PTC1	NP_010278.3	PP2Cc	12..279	CDD:214625	96/301 (32%)