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Protein Alignment CG6036 and PPM1D

DIOPT Version :9

Sequence 1:	NP_651472.2	Gene:	CG6036 / 43185	FlyBaseID:	FBgn0039421	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	NP_003611.1	Gene:	PPM1D / 8493	HGNCID:	9277	Length:	605	Species:	Homo sapiens

Alignment Length:	391	Identity:	104/391 - (26%)
Similarity:	161/391 - (41%)	Gaps:	93/391 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 SAACRLKDPFATWSYFAVFDGHAGSQISLHCAEHLMSTILESESFSKH---KYEAGIREGFLQLD 106
            |..||.:...|   :|||.|||.|.:.:....|||...|.:.:.|:..   |..|.||:|||...
Human    89 SRCCRRRSSVA---FFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPAKVCAAIRKGFLACH 150

  Fly   107 EDMRKLYHD---------QQGGSTAICVFVSPDKIYLVNCGDSRAVISRNG-------AAVISTI 155
            ..|.|...:         ...|:||..|.:...|:|:.:.|||..|:....       .||..|.
Human   151 LAMWKKLAEWPKTMTGLPSTSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQ 215

  Fly   156 DHKPFSPKEQERIQNAGGSVM----IKRI---------NGT------------LAVSRAFGD--- 192
            ||||..|||:|||:..|||||    :.|:         ||.            |||:||.||
Human   216 DHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALGDLWS 280

  Fly   193 YDFKNDGSKSPVDQMVSPEPDIIV--CNRSEHDEFIVVACDGIWDVMTSSEVCEFIRSRLLVTYD 255
            |||.:.      :.:||||||..|  .:..:| ::|::..||:|:::...:.....:.:....|.
Human   281 YDFFSG------EFVVSPEPDTSVHTLDPQKH-KYIILGSDGLWNMIPPQDAISMCQDQEEKKYL 338

  Fly   256 L--------PMIVNSVLDICLHKGSR-DNMTLLLLLLPGAPKVDMDAVKAERSLDQTIVQITKEV 311
            :        .|:||..|.....:..| ||.:.:::.:  :|:||........  |:..:.:|
Human   339 MGEHGQSCAKMLVNRALGRWRQRMLRADNTSAIVICI--SPEVDNQGNFTNE--DELYLNLT--- 396

  Fly   312 IEKHEIHDFETLIRLMKRMAINIPNLPPGGGL------------YAKYYIIEQAFHEKFPDTPAE 364
             :....:..||.:     |..:..:.||...|            :....:...||.|.|.:..||
Human   397 -DSPSYNSQETCV-----MTPSPCSTPPVKSLEEDPWPRVNSKDHIPALVRSNAFSENFLEVSAE 455

  Fly   365 I 365
            |
Human   456 I 456

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.