DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6036 and Ppm1m

DIOPT Version :9

Sequence 1:	NP_651472.2	Gene:	CG6036 / 43185	FlyBaseID:	FBgn0039421	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	NP_080723.3	Gene:	Ppm1m / 67905	MGIID:	1915155	Length:	462	Species:	Mus musculus

Alignment Length:	338	Identity:	75/338 - (22%)
Similarity:	125/338 - (36%)	Gaps:	109/338 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 EKPE-TEKQAQEGHGNGLRYCVSSMQGWRLEMEDSHSAACRLKDPFATWSYFAVFDGHAGSQISL 73
            ||.| .|.||..|     :.|:...: :.:|........|  .:.|.|..|:|:||||.|...::
Mouse    80 EKSEFNEDQAACG-----KLCIRRCE-FGIEEHQEWLTVC--PEEFLTGHYWALFDGHGGPAAAI 136

  Fly    74 HCAEHLMSTI--------------------------------LESESFSKHKYEAGIREGFLQLD 106
            ..|..|.|.:                                :|.:.........|..|...|..
Mouse   137 LAANTLHSCLRRQLEAVVEGMIAPQPPMHLSGRCVCPSDPQFVEEKGIQAEDLVIGALENAFQEC 201

  Fly   107 EDM--RKL-YHDQQGGSTAICVFVSPDKIYLVNCGDSRAV-ISRNGAAVISTIDHKPFSPK-EQE 166
            :|:  |:| ...|.||.||:.......|:|:.|.|||||: :.|:....:|:    .|:|: |::
Mouse   202 DDVIGRELEASGQVGGCTALVAVFLQGKLYVANAGDSRAILVRRHEIRQLSS----EFTPETERQ 262

  Fly   167 RIQ--------------------------NAGGSVMIK--------------------------- 178
            |||                          :.|..|:.:
Mouse   263 RIQQLAFTYPELLAGEFTRLEFPRRLKGDDLGQKVLFRDHHMRGWSYKRVEKSDLKYPLIHGQGR 327

  Fly   179 --RINGTLAVSRAFGDYDFKNDGSKSPVDQMVSPEPDIIVCN----RSEHDEFIVVACDGIWDVM 237
              |:.|||||||..||:..:...:...:...:...|.:.|.:    ..:.::.:|:|.||:|||:
Mouse   328 QARLLGTLAVSRGLGDHQLRVLDTDIQLKPFLLSIPQVTVLDVHQLAVQEEDVVVMATDGLWDVL 392

  Fly   238 TSSEVCEFIRSRL 250
            ::.:|...:||.|
Mouse   393 SNEQVALLVRSFL 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6036	NP_651472.2	PP2Cc	27..277	CDD:238083	68/320 (21%)
CG6036	NP_651472.2	PP2C_C	284..352	CDD:285117
Ppm1m	NP_080723.3	PP2Cc	109..452	CDD:238083	66/303 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834851
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840