DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6036 and ppm1nb

DIOPT Version :9

Sequence 1:	NP_651472.2	Gene:	CG6036 / 43185	FlyBaseID:	FBgn0039421	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	NP_001096587.1	Gene:	ppm1nb / 564875	ZFINID:	ZDB-GENE-071004-34	Length:	435	Species:	Danio rerio

Alignment Length:	360	Identity:	150/360 - (41%)
Similarity:	232/360 - (64%)	Gaps:	10/360 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 FLEKPETEKQAQEGHGN-GLRYCVSSMQGWRLEMEDSHSAACRLKDPFATWSYFAVFDGHAGSQI 71
            :|::|..:|..|||..: ||.|.::||||||..|||.|:...:|....:.|::||||||||||.:
Zfish    58 YLDRPVLDKHMQEGCASWGLTYALASMQGWRAHMEDFHNCFPQLGGELSHWAFFAVFDGHAGSAV 122

  Fly    72 SLHCAEHLMSTILESESF----SKHKYEAGIREGFLQLDEDMRKLYHD---QQGGSTAICVFVSP 129
            :.:|:.:|:..||.:...    ...:...|.:|||..:|:.:..:...   ::||:|.:...::|
Zfish   123 AQNCSRNLLDHILGTGKIRADEDVERVTEGFKEGFFLMDKHLHAMACREGWERGGTTVVSTAITP 187

  Fly   130 DKIYLVNCGDSRAVISRNGAAVISTIDHKPFSPKEQERIQNAGGSVMIKRINGTLAVSRAFGDYD 194
            ..||.|||||||||:.|.|....||.|||||||.|:|||::|||||.::|:||:||||||.||:.
Zfish   188 HHIYFVNCGDSRAVLCRAGRVAFSTEDHKPFSPGEKERIESAGGSVTLQRVNGSLAVSRALGDFS 252

  Fly   195 FKNDGSKSPVDQMVSPEPDIIVCNRSEHDEFIVVACDGIWDVMTSSEVCEFIRSRLLVTYDLPMI 259
            :|....:|..:|||||||::.|..||..|||:|:||||:||.:::.|:|.|:.|||.:..||..:
Zfish   253 YKTVEWRSVTEQMVSPEPEVSVVERSPADEFLVLACDGVWDTVSNEELCAFVHSRLRICTDLREV 317

  Fly   260 VNSVLDICLHKGSRDNMTLLLLLLPGAPKVDMDAVKAERSLDQTIVQITKEVIEKHEIH-DFETL 323
            .:.|:|:||:|||.||::::|:..||||::..:|:..|..|:..:.....|:.|:..:. |...|
Zfish   318 CSQVIDLCLYKGSLDNISIILVCFPGAPQLSPEALHHEAELEDFLESKVAEIFEELSMRGDEPDL 382

  Fly   324 IRLMKRMAIN-IPNLPPGGGLYAKYYIIEQAFHEK 357
            :.::..:|.. ||.|||||||.:|...|..|::::
Zfish   383 LSVLTVLASTVIPGLPPGGGLQSKRNCIISAYYQQ 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6036	NP_651472.2	PP2Cc	27..277	CDD:238083	117/256 (46%)
CG6036	NP_651472.2	PP2C_C	284..352	CDD:285117	23/69 (33%)
ppm1nb	NP_001096587.1	PP2Cc	79..341	CDD:238083	118/261 (45%)
ppm1nb	NP_001096587.1	PP2C_C	335..412	CDD:285117	24/76 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577933
Domainoid	1	1.000	61	1.000	Domainoid score	I10412
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D262211at33208
OrthoFinder	1	1.000	-	-		FOG0000692
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47992
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X444
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.810