DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6036 and si:ch211-15p9.2

DIOPT Version :9

Sequence 1:	NP_651472.2	Gene:	CG6036 / 43185	FlyBaseID:	FBgn0039421	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	NP_001038455.2	Gene:	si:ch211-15p9.2 / 562650	ZFINID:	ZDB-GENE-060503-577	Length:	505	Species:	Danio rerio

Alignment Length:	315	Identity:	77/315 - (24%)
Similarity:	114/315 - (36%)	Gaps:	108/315 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 EDSHSAACRLKDPFATWSYFAVFDGHAGSQISLHCAEHL----------MSTILESES------- 88
            ||..|||..|:   :....|.||||||||..:...:|.|          :.|::|.|:
Zfish   104 EDRRSAATCLQ---SRGMLFGVFDGHAGSACAQAVSERLFYYIALSLLPLRTLMEIEAAVESERP 165

  Fly    89 ----FSKHKY-----------------------------------EAGIREGFLQLDEDMR---- 110
                ...||:                                   :...|..|.:||.|:.
Zfish   166 VLPVLQWHKHPNDYQSTDSGKLYFSSLRTYWQERIDLQENEDCDTQGAFRNAFKRLDNDISLEAQ 230

  Fly   111 -----KLYHDQQ-----GGSTAICVFVSPDKIYLVNCGDSRAVIS-RNG----AAVISTIDHKPF 160
                 .|.|...     .|.||...:|..|.:|:.|.||||||:. :.|    :|...|.||...
Zfish   231 VDIGVPLAHFTPLRVALSGCTACVAYVDQDDLYIANLGDSRAVLGVQQGDGKWSAFTITNDHNAQ 295

  Fly   161 SPKEQERIQN----AGGSVMIK--RINGTLAVSRAFGDYDFK-------------------NDGS 200
            :|.|.:|:.:    .....::|  |:.|.|...|||||..||                   |:.:
Zfish   296 NPNEMKRVLSEHPACEQKTVVKHDRLLGLLIPFRAFGDMKFKWSSELLNRIYEARPELLIGNENA 360

  Fly   201 KS-PVDQMVSP----EPDIIVCNRSEHDEFIVVACDGIWDVMTSSEVCEFIRSRL 250
            |. |.:....|    ||:|........|:|:::..||:|::|....|.:.|...|
Zfish   361 KMLPANYHTPPYLTAEPEITYHKLRPQDKFLILGTDGLWELMHRQTVVQVIGEHL 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6036	NP_651472.2	PP2Cc	27..277	CDD:238083	77/315 (24%)
CG6036	NP_651472.2	PP2C_C	284..352	CDD:285117
si:ch211-15p9.2	NP_001038455.2	PP2Cc	89..501	CDD:238083	77/315 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810