DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6036 and CG15035

DIOPT Version :9

Sequence 1:	NP_651472.2	Gene:	CG6036 / 43185	FlyBaseID:	FBgn0039421	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	NP_572396.1	Gene:	CG15035 / 31673	FlyBaseID:	FBgn0029949	Length:	374	Species:	Drosophila melanogaster

Alignment Length:	379	Identity:	76/379 - (20%)
Similarity:	115/379 - (30%)	Gaps:	145/379 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 HKMGGFLEK------PETEKQAQEGHGNGLRYCVSSMQGWRLEMEDSHSAACRLKDPFATWSY-- 59
            ||.|..|.:      ||. .|..|..|||   .:|..|..||             ||..:..|
  Fly    36 HKGGQVLNRLKGASFPEL-AQNSENIGNG---SMSENQNQRL-------------DPMTSAQYTT 83

  Fly    60 --FAVFDGHAG-------------SQISLHCA---------EHLMSTILESESFSKHKYEA---G 97
              |..|||...             ..:|:.|.         |:......|...|.....:|   |
  Fly    84 LGFGNFDGEGDYLRQKNKINIQLPRLVSVTCGFAKDHIRYPEYNRGKFGEDAWFMSSSPQACIMG 148

  Fly    98 IREGF--------------LQLDEDMRKLYH---------------------DQQ---GGSTAIC 124
            :.:|.              :.|.....::.|                     ||:   .||...|
  Fly   149 VADGVGGWRNYGVDPGKFSMTLMRSCERMSHAPDFKPNRPEILLERAYFDLLDQKCPIVGSCTAC 213

  Fly   125 VFV---SPDKIYLVNCGDSRAVISRNGAAVISTIDHKPFSPKEQERIQNAGGSVMIKRINGTLAV 186
            :..   ....:|..|.|||..::.|:|..|..:        :||:...|....         ||.
  Fly   214 ILALKRDDSTLYAANIGDSGFLVVRSGKVVCRS--------QEQQHQFNTPYQ---------LAS 261

  Fly   187 SRAFGDYDFKNDGSKSPVDQMVSPEPDIIVCNRSEHDEFIVVACDGIWDVMTSSEVCEFI--RSR 249
            .....|:|..:||.:| .|.:..|         .:..:.|::|.||::|.:..|.:.|.:  .|.
  Fly   262 PPPGYDFDAVSDGPES-ADTIQFP---------MQLGDVILLATDGVYDNVPESFLVEVLTEMSG 316

  Fly   250 LLVTYDLPMIVNSVL-----------------------DICLHKGSRDNMTLLL 280
            :.....|.|..|:|.                       ||....|..|::|:||
  Fly   317 ISNPVRLQMAANTVALMARTLSFSPKHDSPFSQNARKHDIDAWGGKPDDITVLL 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6036	NP_651472.2	PP2Cc	27..277	CDD:238083	62/344 (18%)
CG6036	NP_651472.2	PP2C_C	284..352	CDD:285117
CG15035	NP_572396.1	PP2Cc	133..371	CDD:294085	51/265 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900