DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6036 and Ppm1b

DIOPT Version :9

Sequence 1:	NP_651472.2	Gene:	CG6036 / 43185	FlyBaseID:	FBgn0039421	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	NP_001152968.1	Gene:	Ppm1b / 19043	MGIID:	101841	Length:	477	Species:	Mus musculus

Alignment Length:	372	Identity:	188/372 - (50%)
Similarity:	251/372 - (67%)	Gaps:	17/372 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 MGGFLEKPETEKQAQEGHGNGLRYCVSSMQGWRLEMEDSHSAACRLKDPFATWSYFAVFDGHAGS 69
            ||.||:||:|||....|.||||||.:|||||||:||||:|:|...:......||:|||:||||||
Mouse     1 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLDNWSFFAVYDGHAGS 65

  Fly    70 QISLHCAEHLMSTILESESF------------SKHKYEAGIREGFLQLDEDMRKLYHDQQG---- 118
            :::.:|:.||:..|..:|.|            |....:.|||.|||::||.||.....:.|
Mouse    66 RVANYCSTHLLEHITTNEDFRAADKSGSALEPSVESVKTGIRTGFLKIDEYMRNFSDLRNGMDRS 130

  Fly   119 GSTAICVFVSPDKIYLVNCGDSRAVISRNGAAVISTIDHKPFSPKEQERIQNAGGSVMIKRINGT 183
            ||||:.|.|||..:|.:||||||||:.|||....||.||||.:|.|:||||||||||||:|:||:
Mouse   131 GSTAVGVMVSPTHMYFINCGDSRAVLCRNGQVCFSTQDHKPCNPVEKERIQNAGGSVMIQRVNGS 195

  Fly   184 LAVSRAFGDYDFKNDGSKSPVDQMVSPEPDIIVCNRSEHDEFIVVACDGIWDVMTSSEVCEFIRS 248
            ||||||.||||:|....|.|.:|:|||||::....|:|.|||:|:|||||||||::.|:|||::|
Mouse   196 LAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEIVRAEEDEFVVLACDGIWDVMSNEELCEFVKS 260

  Fly   249 RLLVTYDLPMIVNSVLDICLHKGSRDNMTLLLLLLPGAPKVDMDAVKAERSLDQTIVQITKEVIE 313
            ||.|:.||..:.|.|:|.||||||||||:::|:....||||..:|||.:..||:.:....:|:::
Mouse   261 RLEVSDDLENVCNWVVDTCLHKGSRDNMSVVLVCFSNAPKVSEEAVKRDSELDKHLESRVEEIMQ 325

  Fly   314 KHEIHDFETLIRLMKRM-AINIPNLPPGGGLYAKYYIIEQAFHEKFP 359
            |........|..:|:.: |.|||||||||||..|.::||..:....|
Mouse   326 KSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKRHVIEAVYSRLNP 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6036	NP_651472.2	PP2Cc	27..277	CDD:238083	143/265 (54%)
CG6036	NP_651472.2	PP2C_C	284..352	CDD:285117	27/68 (40%)
Ppm1b	NP_001152968.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20		10/18 (56%)
		PP2Cc	23..295	CDD:238083	145/271 (54%)
		PP2C_C	289..365	CDD:369544	28/75 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	58	1.000	Domainoid score	I10718
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53745
OrthoDB	1	1.010	-	-		D262211at33208
OrthoFinder	1	1.000	-	-		FOG0000692
OrthoInspector	1	1.000	-	-		mtm8879
orthoMCL	1	0.900	-	-		OOG6_100270
Panther	1	1.100	-	-	O	PTHR47992
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X444
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.790