Protein Alignment Nil and Ppm1a

DIOPT Version :10

• Sequence 1: NP_651472.2
• Gene: Nil / 43185
• FlyBaseID: FBgn0039421
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: XP_036013148.1
• Gene: Ppm1a / 19042
• MGIID: 99878
• Length: 454
• Species: Mus musculus
• Alignment Length: 380
• Identity: 188/380 - (49%)
• Similarity: 256/380 - (67%)
• Gaps: 18/380 - (4%)

  Fly     5 MGGFLEKPETEKQAQEGHGNGLRYCVSSMQGWRLEMEDSHSAACRLKDPFATWSYFAVFDGHAGS 69
            ||.||:||:.||...:|.||||||.:|||||||:||||:|:|...|.....|||:|||:||||||
Mouse    73 MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLETWSFFAVYDGHAGS 137

  Fly    70 QISLHCAEHLMSTILESESF-------SKHKYEAGIREGFLQLDEDMRKLYHDQQG----GSTAI 123
            |::.:|.|||:..|..::.|       |....:.|||.|||::||.||.:...:.|    ||||:
Mouse   138 QVAKYCCEHLLDHITNNQDFRGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKHGADRSGSTAV 202

  Fly   124 CVFVSPDKIYLVNCGDSRAVISRNGAAVISTIDHKPFSPKEQERIQNAGGSVMIKRINGTLAVSR 188
            .|.:||...|.:||||||.::.||......|.||||.:|.|:||||||||||||:|:||:|||||
Mouse   203 GVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQRVNGSLAVSR 267

  Fly   189 AFGDYDFKNDGSKSPVDQMVSPEPDIIVCNRSEH-DEFIVVACDGIWDVMTSSEVCEFIRSRLLV 252
            |.||:|:|....|.|.:|:|||||::....|||. |:||::|||||||||.:.|:|:|:||||.|
Mouse   268 ALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEV 332

  Fly   253 TYDLPMIVNSVLDICLHKGSRDNMTLLLLLLPGAPKVDMDAVKAERSLDQTIVQITKEVIEKHEI 317
            |.||..:.|.|:|.||:|||||||:::|:..|.||||..:|||.|..||:.:....:|:|:| ::
Mouse   333 TDDLEKVCNEVVDTCLYKGSRDNMSVILICFPSAPKVSAEAVKKEAELDKYLESRVEEIIKK-QV 396

  Fly   318 HDFETLIRLMKRMAI-NIPNLPPGGGLYAKYYIIEQAFHEKFP----DTPAEIYD 367
            .....|:.:|:.:|. |||:|||||.|.:|..:||..::...|    ||.:...|
Mouse   397 EGVPDLVHVMRTLASENIPSLPPGGELASKRNVIEAVYNRLNPYKNDDTDSASTD 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nil	NP_651472.2	PP2Cc	27..277	CDD:238083	140/261 (54%)
		PP2C_C	284..355	CDD:429684	29/71 (41%)
Ppm1a	XP_036013148.1	PP2Cc	95..363	CDD:238083	142/267 (53%)
		PP2C_C	357..435	CDD:429684	30/78 (38%)