DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6036 and ppm-1.A

DIOPT Version :9

Sequence 1:	NP_651472.2	Gene:	CG6036 / 43185	FlyBaseID:	FBgn0039421	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	NP_001023842.1	Gene:	ppm-1.A / 179469	WormBaseID:	WBGene00006460	Length:	468	Species:	Caenorhabditis elegans

Alignment Length:	357	Identity:	156/357 - (43%)
Similarity:	222/357 - (62%)	Gaps:	30/357 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 MGGFLEKPETEKQAQEGHGNGLRYCVSSMQGWRLEMEDSHSAACRL--KDPFATWSYFAVFDGHA 67
            ||.||:||:|:|....|.|||:||.:|||||||:.|||||.|...:  ..|:..||:||||||||
Worm    84 MGAFLDKPKTDKTNVHGEGNGIRYGMSSMQGWRICMEDSHIAEAIMSQSSPYKDWSFFAVFDGHA 148

  Fly    68 GSQISLHCAEHLMSTILESESFSK-----------------HKYEAGIREGFLQLDEDMRKLYHD 115
            |..|:...:..|:..::.||.|.:                 ...|.||::|||..||..:.....
Worm   149 GHHIANRASSQLLEHLISSEEFREMTKTLEENNGVLTDSTLKLLEKGIKKGFLSFDEISKTSNDI 213

  Fly   116 QQGGSTAICVFVSPDKIYLVNCGDSRAVISRNGAAVISTIDHKPFSPKEQERIQNAGGSVMIKRI 180
            .:.|.||:|..|:|....:.|.||||||::... .:..|.||||:..||::||:.|||||||:||
Worm   214 SKSGCTAVCAIVTPTHFIIGNLGDSRAVVAGKN-EIFGTEDHKPYLEKERKRIEGAGGSVMIQRI 277

  Fly   181 NGTLAVSRAFGDYDFKNDGSKSPVD-QMVSPEPDIIVCNRS-EHDEFIVVACDGIWDVMTSSEVC 243
            ||:||||||||||::|:| .:.|.| |:||||||:.:..|: |:|:|:|||||||:||||:.|:.
Worm   278 NGSLAVSRAFGDYEYKDD-PRLPADQQLVSPEPDVYIRERNLENDQFMVVACDGIYDVMTNEELA 341

  Fly   244 EFIRSRLLVTYDLPMIVNSVLDICLHKGSRDNMTLLLLLLPGAPKVDMDAVKAER---SLDQTIV 305
            ||::.||.|..||..:.:.|||.||.||||||||::::..|.||:|::...:||.   |..:|::
Worm   342 EFVKDRLSVHSDLREVCDDVLDECLVKGSRDNMTMVVVCFPAAPEVNIHRKEAEEAWVSRVKTVI 406

  Fly   306 -QITKEVIEKHEI---HDFETLIRLMKRMAIN 333
             |...|.:...:.   .|..||..::.::..|
Worm   407 NQFLDEAVAAEDFKQEEDMVTLKSILDKVTAN 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6036	NP_651472.2	PP2Cc	27..277	CDD:238083	128/270 (47%)
CG6036	NP_651472.2	PP2C_C	284..352	CDD:285117	14/57 (25%)
ppm-1.A	NP_001023842.1	PP2C	105..374	CDD:366121	127/270 (47%)
ppm-1.A	NP_001023842.1	PP2C_C	375..>412	CDD:392186	10/36 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156328
Domainoid	1	1.000	235	1.000	Domainoid score	I1321
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	281	1.000	Inparanoid score	I1754
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53745
OrthoDB	1	1.010	-	-		D262211at33208
OrthoFinder	1	1.000	-	-		FOG0000692
OrthoInspector	1	1.000	-	-		otm14106
orthoMCL	1	0.900	-	-		OOG6_100270
Panther	1	1.100	-	-	O	PTHR47992
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X444
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.910