DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6036 and PPM1L

DIOPT Version :9

Sequence 1:NP_651472.2 Gene:CG6036 / 43185 FlyBaseID:FBgn0039421 Length:371 Species:Drosophila melanogaster
Sequence 2:NP_640338.2 Gene:PPM1L / 151742 HGNCID:16381 Length:360 Species:Homo sapiens


Alignment Length:312 Identity:91/312 - (29%)
Similarity:155/312 - (49%) Gaps:49/312 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 KMGGF--LEKPETEKQAQEGHGNGLRYCVSSMQGWRLEMEDSHSAACRLKD---PFATWSYFAVF 63
            ::||.  ||...::....:.|    ...|.|:||.|..|||.......|.:   |    |.|.:|
Human    71 RLGGLDVLEAEFSKTWEFKNH----NVAVYSIQGRRDHMEDRFEVLTDLANKTHP----SIFGIF 127

  Fly    64 DGHAGSQISLHCAEHLMSTILES-----ESFSKHK------YEAGIREGFLQLDEDMRK---LYH 114
            |||.|..    .||::.|.:.|:     :.:.|.|      |:..:.:..|.:|.:|.:   :.:
Human   128 DGHGGET----AAEYVKSRLPEALKQHLQDYEKDKENSVLSYQTILEQQILSIDREMLEKLTVSY 188

  Fly   115 DQQGGSTAICVFVSPDKIYLVNCGDSRAVI-SRNGAAVISTIDHKPFSPKEQERIQNAGGSVMIK 178
            | :.|:|.:...:|...:.:.|.||||.|: .::|.|:..:.||||:..||::||:.|||.:...
Human   189 D-EAGTTCLIALLSDKDLTVANVGDSRGVLCDKDGNAIPLSHDHKPYQLKERKRIKRAGGFISFN 252

  Fly   179 ---RINGTLAVSRAFGDYDFKNDGSKSPVDQMVSPEPDIIVCNRSE-HDEFIVVACDGIWDVMTS 239
               |:.|.||:||:.|||..||       ..:|.|:|||:..:..: ..||:::|.||:||..::
Human   253 GSWRVQGILAMSRSLGDYPLKN-------LNVVIPDPDILTFDLDKLQPEFMILASDGLWDAFSN 310

  Fly   240 SEVCEFIRSRLLVTYDLPMI-VNSVLDICLHKGSRDNMTLLLLLLPGAPKVD 290
            .|...||:.||    |.|.. ..|::....::|..||:|::::....:.|.:
Human   311 EEAVRFIKERL----DEPHFGAKSIVLQSFYRGCPDNITVMVVKFRNSSKTE 358

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6036NP_651472.2 PP2Cc 27..277 CDD:238083 84/272 (31%)
PP2C_C 284..352 CDD:285117 1/7 (14%)
PPM1LNP_640338.2 PP2Cc 93..351 CDD:238083 85/277 (31%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0631
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53745
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

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