DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6154 and Dpep1

DIOPT Version :9

Sequence 1:	NP_651471.2	Gene:	CG6154 / 43184	FlyBaseID:	FBgn0039420	Length:	434	Species:	Drosophila melanogaster
Sequence 2:	NP_446043.1	Gene:	Dpep1 / 94199	RGDID:	620324	Length:	410	Species:	Rattus norvegicus

Alignment Length:	376	Identity:	197/376 - (52%)
Similarity:	247/376 - (65%)	Gaps:	16/376 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 FRMQRVRNVLKEVPLIDGHNDLPWNIRKFLKNQLKDFHFGGDLRELAPWSSSAWSHTDLRRLKEG 117
            ||.| ..|:::..|:|||||||||.:.....|||:        :..|..|:.|.:||::.:|:.|
  Rat    19 FRNQ-AENIMRTTPVIDGHNDLPWQMLTLFNNQLR--------KSEANLSALAETHTNIPKLRAG 74

  Fly   118 MVSAQFWSAYAPCSSQHLDAVQLTLEQIDLIRRLVQLYPHHMALVTTASGIEQTHRTGKIASLIG 182
            .|..||||||.||.:|:.|||:..|||||:|.|:.||||.....||.:|.|.|..|.||:|||||
  Rat    75 FVGGQFWSAYMPCDTQNKDAVKRILEQIDVIHRMCQLYPETFECVTNSSDILQAFRRGKVASLIG 139

  Fly   183 VEGGHAIGTSLSVLRMFYQLGARYLTLTHTCNTPWADCCKVDEPGKYPHIGGLSQFGKLVVKEMN 247
            |||||.|.:||.|||..|.||.|||||||.|||||||...||:........|||.|||||:.|||
  Rat   140 VEGGHLIDSSLGVLRTLYHLGMRYLTLTHNCNTPWADNWLVDKGDDEAESQGLSPFGKLVLNEMN 204

  Fly   248 RLGMIVDLSHVSVPTMLDALAASRAPLIFSHSSAHAICNSSRNVPDHVLQRIAINGGLVMVAFYP 312
            |||:::|||||||.||.|||..|:||:|||||||:::|...|||||.|||.:.....||||.||.
  Rat   205 RLGVMIDLSHVSVATMKDALQLSKAPVIFSHSSAYSVCPHRRNVPDDVLQLVKSTNSLVMVNFYN 269

  Fly   313 HFVSCSGQATLHDVVAHINHIREVAGIDHVGIGAGYDGVNLVPKGLEDVSKYPHLFAALLESDKW 377
            .|||||..|||..|..|::||::|||...||:|..||||..:|.|||||||||.|.|.||..: |
  Rat   270 QFVSCSDSATLSQVADHLDHIKKVAGAGAVGLGGDYDGVTNLPVGLEDVSKYPDLIAELLRRN-W 333

  Fly   378 SEEDIAKLAGRNLIRVFKEVEAVRDQMELLRVAPIDQSIPAEDIMGRSYCR 428
            :|.::..|...||:|||..||.|.:.|::    |.:::||.|.:.|.  ||
  Rat   334 TETEVRGLLAENLLRVFSAVELVSNIMQV----PEEETIPVEKLDGS--CR 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6154	NP_651471.2	Peptidase_M19	61..396	CDD:395996	182/334 (54%)
Dpep1	NP_446043.1	Peptidase_M19	26..352	CDD:395996	182/334 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349111
Domainoid	1	1.000	351	1.000	Domainoid score	I986
eggNOG	1	0.900	-	-		E1_COG2355
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H80192
Inparanoid	1	1.050	367	1.000	Inparanoid score	I2089
OMA	1	1.010	-	-		QHG53057
OrthoDB	1	1.010	-	-		D1272387at2759
OrthoFinder	1	1.000	-	-		FOG0001225
OrthoInspector	1	1.000	-	-		otm46334
orthoMCL	1	0.900	-	-		OOG6_102004
Panther	1	1.100	-	-	O	PTHR10443
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X677
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770