Protein Alignment CG6154 and DPEP3

DIOPT Version :10

• Sequence 1: NP_651471.2
• Gene: CG6154 / 43184
• FlyBaseID: FBgn0039420
• Length: 434
• Species: Drosophila melanogaster
• Sequence 2: NP_001357127.1
• Gene: DPEP3 / 64180
• HGNCID: 23029
• Length: 488
• Species: Homo sapiens
• Alignment Length: 395
• Identity: 176/395 - (44%)
• Similarity: 240/395 - (60%)
• Gaps: 25/395 - (6%)

  Fly    28 PILRCSAGAASSASGGG---SKTADDFDFRMQRVRNVLKEVPLIDGHNDLPWNIRKFLKNQLKDF 89
            |.|..:.|..|:.:..|   ..|....|.| .|.:.:::..||:|||||||..:|:..||.|:|.
Human    52 PSLFTTPGVPSALTTPGLTTPGTPKTLDLR-GRAQALMRSFPLVDGHNDLPQVLRQRYKNVLQDV 115

  Fly    90 HFGGDLRELAPWSSSAWSH--TDLRRLKEGMVSAQFWSAYAPCSSQHLDAVQLTLEQIDLIRRLV 152
                :||.        :||  |.|.||::|:|.||||||...|.||...||:|.|||||||.|:.
Human   116 ----NLRN--------FSHGQTSLDRLRDGLVGAQFWSASVSCQSQDQTAVRLALEQIDLIHRMC 168

  Fly   153 QLYPHHMALVTTASGIEQTHRTGKIASLIGVEGGHAIGTSLSVLRMFYQLGARYLTLTHTCNTPW 217
            ..| ..:.|||:|.|:..:.   |:|.||||||||::.:||||||.||.||.||||||.||:|||
Human   169 ASY-SELELVTSAEGLNSSQ---KLACLIGVEGGHSLDSSLSVLRSFYVLGVRYLTLTFTCSTPW 229

  Fly   218 ADCCKVDEPGKYPHIGGLSQFGKLVVKEMNRLGMIVDLSHVSVPTMLDALAASRAPLIFSHSSAH 282
            |:.........|.::.||:.||:.||:|:|||||::|||:.|...:...|..|:||:|||||:|.
Human   230 AESSTKFRHHMYTNVSGLTSFGEKVVEELNRLGMMIDLSYASDTLIRRVLEVSQAPVIFSHSAAR 294

  Fly   283 AICNSSRNVPDHVLQRIAINGGLVMVAFYPHFVSCSGQATLHDVVAHINHIREVAGIDHVGIGAG 347
            |:|::..||||.:||.:..|||:|||......:.|:..|.:..|..|.:|||.|.|.:.:|||..
Human   295 AVCDNLLNVPDDILQLLKKNGGIVMVTLSMGVLQCNLLANVSTVADHFDHIRAVIGSEFIGIGGN 359

  Fly   348 YDGVNLVPKGLEDVSKYPHLFAALLESDKWSEEDIAKLAGRNLIRVFKEVEAVRDQMELLRVAPI 412
            |||....|:||||||.||.|...|| |..||||::..:...||:|||::||.||:  |....:|:
Human   360 YDGTGRFPQGLEDVSTYPVLIEELL-SRSWSEEELQGVLRGNLLRVFRQVEKVRE--ESRAQSPV 421

  Fly   413 DQSIP 417
            :...|
Human   422 EAEFP 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6154	NP_651471.2	Peptidase_M19	61..396	CDD:395996	160/336 (48%)
DPEP3	NP_001357127.1	Peptidase_M19	87..407	CDD:395996	160/336 (48%)