DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6154 and CG42750

DIOPT Version :9

Sequence 1:	NP_651471.2	Gene:	CG6154 / 43184	FlyBaseID:	FBgn0039420	Length:	434	Species:	Drosophila melanogaster
Sequence 2:	NP_724101.4	Gene:	CG42750 / 35090	FlyBaseID:	FBgn0261804	Length:	1068	Species:	Drosophila melanogaster

Alignment Length:	418	Identity:	230/418 - (55%)
Similarity:	287/418 - (68%)	Gaps:	8/418 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 KSRKLP-KGFVLCGLNCLTF---VYFPLVLPILRCSAGAASSASGGGSKTADD--FDFRMQRVRN 60
            |.|:.| :|....|.|...|   .::..|..|| ...||||.|.....:.|..  |:.|::....
  Fly   637 KHRQCPSRGSSSSGTNSFRFDAAKHWLAVSSIL-LIIGAASVAVPLALRVAASAPFEERLRVAVQ 700

  Fly    61 VLKEVPLIDGHNDLPWNIRKFLKNQLKDFHFGGDLRELAPWSSSAWSHTDLRRLKEGMVSAQFWS 125
            :|.:||||||||||||||||||.|:|.||:|..|||.:.||..|.||||||.|||:|.:|||||:
  Fly   701 LLDQVPLIDGHNDLPWNIRKFLHNKLNDFNFDEDLRNVMPWGRSHWSHTDLTRLKKGRISAQFWA 765

  Fly   126 AYAPCSSQHLDAVQLTLEQIDLIRRLVQLYPHHMALVTTASGIEQTHRTGKIASLIGVEGGHAIG 190
            ||.||.:||.|||||||||||:|:||...|...:...|:|..|...|:..::.||.||||||::|
  Fly   766 AYVPCEAQHRDAVQLTLEQIDVIKRLTDRYSPQLTTCTSAQDIIDAHKNQQLCSLTGVEGGHSLG 830

  Fly   191 TSLSVLRMFYQLGARYLTLTHTCNTPWADCCKVDEPGKYPHIGGLSQFGKLVVKEMNRLGMIVDL 255
            .||:|||..|.:|.||:|||.||:|||||....|.|......|||:.|||.:::|||||||:|||
  Fly   831 GSLAVLRTLYAIGVRYMTLTSTCHTPWADSSYADAPTFNMKHGGLTIFGKTIIREMNRLGMMVDL 895

  Fly   256 SHVSVPTMLDALAASRAPLIFSHSSAHAICNSSRNVPDHVLQRIAINGGLVMVAFYPHFVSCSGQ 320
            ||||..||.|||..|.||:|||||||:.:||:||||.|.:||.:|.|||||||.||..|:|||..
  Fly   896 SHVSKGTMRDALEVSEAPVIFSHSSAYELCNTSRNVQDDILQALAKNGGLVMVNFYSKFLSCSDN 960

  Fly   321 ATLHDVVAHINHIREVAGIDHVGIGAGYDGVNLVPKGLEDVSKYPHLFAALLESDKWSEEDIAKL 385
            :|:||.|||||||:.||||||||:||||||:|..||||||||.||.|||.|| ...|:.:::.||
  Fly   961 STVHDAVAHINHIKRVAGIDHVGLGAGYDGINYTPKGLEDVSSYPTLFAELL-GGGWTIDELTKL 1024

  Fly   386 AGRNLIRVFKEVEAVRDQMELLRVAPID 413
            ||.|.:||.::||.:||..:...|.|.:
  Fly  1025 AGGNFLRVMQQVEKLRDDKKAAGVKPFE 1052

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6154	NP_651471.2	Peptidase_M19	61..396	CDD:395996	206/334 (62%)
CG42750	NP_724101.4	Peptidase_M19	701..1035	CDD:279569	206/334 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	347	1.000	Domainoid score	I1002
eggNOG	1	0.900	-	-		E1_COG2355
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1272387at2759
OrthoFinder	1	1.000	-	-		FOG0001225
OrthoInspector	1	1.000	-	-		otm26602
orthoMCL	1	0.900	-	-		OOG6_102004
Panther	1	1.100	-	-	P	PTHR10443
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X677
	9	8.820