DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6154 and SPCC965.12

DIOPT Version :9

Sequence 1:	NP_651471.2	Gene:	CG6154 / 43184	FlyBaseID:	FBgn0039420	Length:	434	Species:	Drosophila melanogaster
Sequence 2:	NP_001342728.1	Gene:	SPCC965.12 / 2539107	PomBaseID:	SPCC965.12	Length:	416	Species:	Schizosaccharomyces pombe

Alignment Length:	381	Identity:	164/381 - (43%)
Similarity:	224/381 - (58%)	Gaps:	27/381 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 DDFDFRMQRVRNVLKEVPLIDGHNDLPWNIRKFLKN--QLKDFHFGGDLRELAPWSSSAWSHTDL 111
            ::.:...||.:.:.|...::|.|||.|:.:|..|:|  ||.:|.|...|.          |||||
pombe     7 EEKELAQQRFKEICKHAKIVDTHNDFPYLLRVQLRNKLQLAEFDFENGLT----------SHTDL 61

  Fly   112 RRLKEGMVSAQFWSAYAPCSS-----QHLD----AVQLTLEQIDLIRRLVQLYPHHMALVTTA-S 166
            .::::|.|..||:|.:..|.:     |..|    .|:.||||||:.||||..|.:.:..|..| .
pombe    62 VKMRQGQVGVQFFSCFIECKNPNYLYQDFDTPTTVVRDTLEQIDVTRRLVCKYNNDLKFVDCADD 126

  Fly   167 GIEQTHRTGKIASLIGVEGGHAIGTSLSVLRMFYQLGARYLTLTHTCNTPWADCCKVDEPGKYPH 231
            .|......||||..:||||.|.:.|||:|||.:|.||.||:||||.|:.|:|.... ...|..|.
pombe   127 AIAAFRNNGKIAIALGVEGLHQVDTSLAVLRQYYSLGVRYITLTHNCDNPFATAAS-SITGGLPD 190

  Fly   232 IGGLSQFGKLVVKEMNRLGMIVDLSHVSVPTMLDALAASRAPLIFSHSSAHAICNSSRNVPDHVL 296
             .|||.:|...:.|||||||:|||||||..||.|||..::||:|||||||:.:....|||.|.||
pombe   191 -RGLSAYGIECIFEMNRLGMMVDLSHVSHRTMHDALDVTKAPVIFSHSSAYTLTEHERNVRDDVL 254

  Fly   297 QRIAINGGLVMVAFYPHFVSCSG--QATLHDVVAHINHIREVAGIDHVGIGAGYDGVNLVPKGLE 359
            :|:..|||:|.|.||..|:...|  :||:.|...||.||.:|||.:|||:|:.:||:...|||||
pombe   255 ERLKTNGGVVQVNFYQDFIRKPGSDRATIDDAADHILHIIKVAGWEHVGLGSDFDGIPQGPKGLE 319

  Fly   360 DVSKYPHLFAALLESDKWSEEDIAKLAGRNLIRVFKEVEAVRDQMELLRVAPIDQS 415
            ||||||.|...::|....:.|.|..|.|.|::||:|:.|.|..|:. .::.||:.|
pombe   320 DVSKYPDLICKIIERTNATNEQIEGLMGLNVLRVWKKTELVALQLS-KKLEPIESS 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6154	NP_651471.2	Peptidase_M19	61..396	CDD:395996	155/348 (45%)
SPCC965.12	NP_001342728.1	Peptidase_M19	18..356	CDD:279569	155/349 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	262	1.000	Domainoid score	I361
eggNOG	1	0.900	-	-		E1_COG2355
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I704
OMA	1	1.010	-	-		QHG53057
OrthoFinder	1	1.000	-	-		FOG0001225
OrthoInspector	1	1.000	-	-		mtm9317
orthoMCL	1	0.900	-	-		OOG6_102004
Panther	1	1.100	-	-	O	PTHR10443
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X677
TreeFam	1	0.960	-	-
	11	10.830