DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ald1 and PDE345

DIOPT Version :9

Sequence 1:	NP_001262985.1	Gene:	Ald1 / 43183	FlyBaseID:	FBgn0000064	Length:	363	Species:	Drosophila melanogaster
Sequence 2:	NP_178224.1	Gene:	PDE345 / 814643	AraportID:	AT2G01140	Length:	391	Species:	Arabidopsis thaliana

Alignment Length:	330	Identity:	181/330 - (54%)
Similarity:	223/330 - (67%)	Gaps:	5/330 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 DELREIAQKIVAPGKGILAADESGPTMGKRLQDIGVENTEDNRRAYRQLLFSTDPKLAENISGVI 78
            |||.:.|:.|.:||:||||.|||..|.||||..||::||||||:||||||.:| |.|.:.|||.|
plant    46 DELVKTAKSIASPGRGILAIDESNATCGKRLASIGLDNTEDNRQAYRQLLLTT-PGLGDYISGSI 109

  Fly    79 LFHETLYQKADDGTPFAEILKKKGIILGIKVDKGVVPLFGSEDEVTTQGLDDLAARCAQYKKDGC 143
            ||.|||||...||..|.:.|:...|:.|||||||:.||.||.:|...||||.||:|.|:|.|.|.
plant   110 LFEETLYQSTKDGKTFVDCLRDANIVPGIKVDKGLSPLAGSNEESWCQGLDGLASRSAEYYKQGA 174

  Fly   144 DFAKWRCVLKIGKNTPSYQSILENANVLARYASICQSQRIVPIVEPEVLPDGDHDLDRAQKVTET 208
            .|||||.|:.:... ||..::.|.|..|||||:|.|...:|||||||:|.||||.::|..:|.|.
plant   175 RFAKWRTVVSVPCG-PSALAVKEAAWGLARYAAISQDNGLVPIVEPEILLDGDHPIERTLEVAEK 238

  Fly   209 VLAAVYKALSDHHVYLEGTLLKPNMVTAGQSAK-KNTPEEIALATVQALRRTVPAAVTGVTFLSG 272
            |.:.|:..|:.::|..||.||||:|||.|...| |.:||.:|..|:..|:|.||.||.|:.||||
plant   239 VWSEVFFYLAQNNVMFEGILLKPSMVTPGAEHKNKASPETVADFTLTMLKRRVPPAVPGIMFLSG 303

  Fly   273 GQSEEEATVNLSAINNVPLIRPWALTFSYGRALQASVLRAWAGKKENIAAGQNELLKRAKANSQA 337
            ||||.|||:||:|:|..|  .||.::|||.||||.||||.|.||.|.|.|.|..||.||||||.|
plant   304 GQSEAEATLNLNAMNQSP--NPWHVSFSYARALQNSVLRTWQGKPEKIEASQKALLVRAKANSLA 366

  Fly   338 CQGIY 342
            ..|.|
plant   367 QLGKY 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ald1	NP_001262985.1	Glycolytic	15..363	CDD:278692	180/329 (55%)
PDE345	NP_178224.1	PLN02425	1..391	CDD:215234	181/330 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3588
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63159
OrthoDB	1	1.010	-	-		D799973at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100527
Panther	1	1.100	-	-	O	PTHR11627
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.790