DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ald1 and Aldoart2

DIOPT Version :9

Sequence 1:	NP_001262985.1	Gene:	Ald1 / 43183	FlyBaseID:	FBgn0000064	Length:	363	Species:	Drosophila melanogaster
Sequence 2:	NP_001013965.1	Gene:	Aldoart2 / 299052	RGDID:	1359133	Length:	364	Species:	Rattus norvegicus

Alignment Length:	362	Identity:	249/362 - (68%)
Similarity:	287/362 - (79%)	Gaps:	5/362 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 YP----SKELQDELREIAQKIVAPGKGILAADESGPTMGKRLQDIGVENTEDNRRAYRQLLFSTD 67
            ||    :.|.:.||.:||.:||||||||||||||..::.||||.||.||||:|||.|||||.:.|
  Rat     3 YPYLALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTAD 67

  Fly    68 PKLAENISGVILFHETLYQKADDGTPFAEILKKKGIILGIKVDKGVVPLFGSEDEVTTQGLDDLA 132
            .::...|.||||||||||||.|||.||.:::|.||.::|||||||||.|.|::.|.||||||||:
  Rat    68 DRVNSCIGGVILFHETLYQKTDDGRPFPQVIKSKGGVVGIKVDKGVVTLAGTDGETTTQGLDDLS 132

  Fly   133 ARCAQYKKDGCDFAKWRCVLKIGKNTPSYQSILENANVLARYASICQSQRIVPIVEPEVLPDGDH 197
            .||||||:||.|||||||||||||:|||..:||||||||||||||||...||||||||:||||||
  Rat   133 GRCAQYKQDGADFAKWRCVLKIGKHTPSALAILENANVLARYASICQQNGIVPIVEPEILPDGDH 197

  Fly   198 DLDRAQKVTETVLAAVYKALSDHHVYLEGTLLKPNMVTAGQS-AKKNTPEEIALATVQALRRTVP 261
            ||.|.|.|||.|||||||||||||||||||||||||||.|.: .:|.:.||||:|||.|||||||
  Rat   198 DLKRCQYVTEKVLAAVYKALSDHHVYLEGTLLKPNMVTPGHTCTQKFSSEEIAMATVTALRRTVP 262

  Fly   262 AAVTGVTFLSGGQSEEEATVNLSAINNVPLIRPWALTFSYGRALQASVLRAWAGKKENIAAGQNE 326
            .||.||||||||||||||::||:|||..||::|||||||||||||||.|:||.||:||..|.|.|
  Rat   263 PAVPGVTFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKEENKKAAQEE 327

  Fly   327 LLKRAKANSQACQGIYVPGSIPSFAGNANLFVAQHKY 363
            .:|||.|||.||||.|.|........:.:||::.|.|
  Rat   328 YIKRALANSLACQGKYTPSDESGAVASESLFISNHAY 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ald1	NP_001262985.1	Glycolytic	15..363	CDD:278692	245/348 (70%)
Aldoart2	NP_001013965.1	Glycolytic	15..364	CDD:278692	245/348 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354208
Domainoid	1	1.000	492	1.000	Domainoid score	I353
eggNOG	1	0.900	-	-		E1_COG3588
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H134148
Inparanoid	1	1.050	494	1.000	Inparanoid score	I1340
OMA	1	1.010	-	-		QHG63159
OrthoDB	1	1.010	-	-		D342837at33208
OrthoFinder	1	1.000	-	-		FOG0000633
OrthoInspector	1	1.000	-	-		mtm9110
orthoMCL	1	0.900	-	-		OOG6_100527
Panther	1	1.100	-	-	O	PTHR11627
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X377
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770