DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34129 and PRSS1

DIOPT Version :9

Sequence 1:	NP_001036760.1	Gene:	CG34129 / 43181	FlyBaseID:	FBgn0083965	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	XP_011514713.1	Gene:	PRSS1 / 5644	HGNCID:	9475	Length:	472	Species:	Homo sapiens

Alignment Length:	297	Identity:	67/297 - (22%)
Similarity:	118/297 - (39%)	Gaps:	69/297 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 LLKTPKFRR-----VWGGVQSNTGPNFGGWLLRILNGDGNFACGAAYYA---PLLVIT------- 80
            |::.|..|:     |.|||.:.|..:...|:| :...|.:.....|:..   |||::|
Human   177 LMQDPGKRKAAGVFVLGGVVTLTSQSPPLWIL-VRYKDESSTTSQAHSTTMNPLLILTFVAAALA 240

  Fly    81 -----------SANC---IYPYRNSLEGA--TVEGTAFSE--------CDRENYA------DIDT 115
                       ..||   ..||:.||...  ...|:..:|        |.:....      :|:.
Human   241 APFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEV 305

  Fly   116 IQFPEKFI----------YQK--LYMDVAVVRL--RDPVRGRLTEFIRLCSVKVQPKMQMVVFGW 166
            ::..|:||          |.:  |..|:.:::|  |..:..|::. |.|.:.......:.::.||
Human   306 LEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVST-ISLPTAPPATGTKCLISGW 369

  Fly   167 GFDNTE---VEIPSSDPRNVTVTIISIKECRQKFKSPKIASTSICARQPKNPK-QCLYDGGSPLI 227
            |  ||.   .:.| .:.:.:...::|..:|...:.. ||.|...|....:..| .|..|.|.|::
Human   370 G--NTASSGADYP-DELQCLDAPVLSQAKCEASYPG-KITSNMFCVGFLEGGKDSCQGDSGGPVV 430

  Fly   228 YGRELCGVVSFGSHCIDTSRPGMYTNIRRVKRFITET 264
            ...:|.||||:|..|...::||:||.:....::|..|
Human   431 CNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNT 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34129	NP_001036760.1	Tryp_SPc	39..261	CDD:214473	62/284 (22%)
CG34129	NP_001036760.1	Tryp_SPc	55..261	CDD:304450	57/263 (22%)
PRSS1	XP_011514713.1	Ig	19..119	CDD:299845
		IG_like	29..113	CDD:214653
		Tryp_SPc	248..464	CDD:214473	49/220 (22%)
		Tryp_SPc	249..467	CDD:238113	50/222 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBP0
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810