DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34129 and PROC

DIOPT Version :9

Sequence 1:	NP_001036760.1	Gene:	CG34129 / 43181	FlyBaseID:	FBgn0083965	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	XP_024308770.1	Gene:	PROC / 5624	HGNCID:	9451	Length:	576	Species:	Homo sapiens

Alignment Length:	233	Identity:	56/233 - (24%)
Similarity:	90/233 - (38%)	Gaps:	48/233 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 WLLRILNGDGNFACGAAYYAPLLVITSANCIYPYRNSLEGATVEGTAFSECDRENYA--DIDTIQ 117
            |.:.:|:.....||||....|..|:|:|:|:...:..|       ....|.|...:.  ::| :.
Human   340 WQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLL-------VRLGEYDLRRWEKWELD-LD 396

  Fly   118 FPEKFI---YQKLYM--DVAVVRLRDPVRGRLTEFIRLCSVKV--------QPKMQMVVFGWGFD 169
            ..|.|:   |.|...  |:|::.|..|.....| .:.:|....        |...:.:|.|||:.
Human   397 IKEVFVHPNYSKSTTDNDIALLHLAQPATLSQT-IVPICLPDSGLAERELNQAGQETLVTGWGYH 460

  Fly   170 NTEVEIPSSDPRNVTVTIISIK-------ECRQKFKSPKIASTSICA-----RQPKNPKQCLYDG 222
            ::.   .....||.|..:..||       || .:..|..::...:||     ||    ..|..|.
Human   461 SSR---EKEAKRNRTFVLNFIKIPVVPHNEC-SEVMSNMVSENMLCAGILGDRQ----DACEGDS 517

  Fly   223 GSPLIYGRE----LCGVVSFGSHCIDTSRPGMYTNIRR 256
            |.|::....    |.|:||:|..|......|:||.:.|
Human   518 GGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTKVSR 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34129	NP_001036760.1	Tryp_SPc	39..261	CDD:214473	56/233 (24%)
CG34129	NP_001036760.1	Tryp_SPc	55..261	CDD:304450	56/233 (24%)
PROC	XP_024308770.1	GLA	117..168	CDD:214503
		EGF_CA	182..213	CDD:238011
		FXa_inhibition	255..290	CDD:317114
		Tryp_SPc	328..563	CDD:238113	56/233 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910