DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34129 and CFI

DIOPT Version :9

Sequence 1:	NP_001036760.1	Gene:	CG34129 / 43181	FlyBaseID:	FBgn0083965	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	NP_001362207.1	Gene:	CFI / 3426	HGNCID:	5394	Length:	601	Species:	Homo sapiens

Alignment Length:	153	Identity:	38/153 - (24%)
Similarity:	61/153 - (39%)	Gaps:	26/153 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 RRVWGGVQSNTG--PNFGGWLLRILNGDGNFACGAAYYAPLLVITSANCI---YPYRNSLEGATV 97
            :|:.||.::..|  |    |.:.|.:..| ..||..|.....::|:|:|:   ..:|..: ..||
Human   346 KRIVGGKRAQLGDLP----WQVAIKDASG-ITCGGIYIGGCWILTAAHCLRASKTHRYQI-WTTV 404

  Fly    98 EGTAFSECDRENYADIDTIQFPEKF---IYQKLYMDVAVVRLRDPVRGRLTEFIRLCSVKV---- 155
            ......:..|.....:|.|.|.|.:   .||.   |:|::.::.....:..|..|.....|
Human   405 VDWIHPDLKRIVIEYVDRIIFHENYNAGTYQN---DIALIEMKKDGNKKDCELPRSIPACVPWSP 466

  Fly   156 ---QPKMQMVVFGWG--FDNTEV 173
               ||....:|.|||  .||..|
Human   467 YLFQPNDTCIVSGWGREKDNERV 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34129	NP_001036760.1	Tryp_SPc	39..261	CDD:214473	38/152 (25%)
CG34129	NP_001036760.1	Tryp_SPc	55..261	CDD:304450	33/134 (25%)
CFI	NP_001362207.1	FIMAC	43..108	CDD:214493
		SR	114..215	CDD:214555
		LDLa	224..256	CDD:238060
		Ldl_recept_a	257..293	CDD:365841
		Tryp_SPc	348..>519	CDD:238113	37/151 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910