DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34129 and PRSS53

DIOPT Version :9

Sequence 1:	NP_001036760.1	Gene:	CG34129 / 43181	FlyBaseID:	FBgn0083965	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	XP_011544118.1	Gene:	PRSS53 / 339105	HGNCID:	34407	Length:	623	Species:	Homo sapiens

Alignment Length:	319	Identity:	64/319 - (20%)
Similarity:	99/319 - (31%)	Gaps:	113/319 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 QSNTGPNFGGWLLRILNGDGNFACGAAYYAPLLVITSANCIYPYRNSLEGATVEGTAFS----EC 105
            :.||.|....|...: ...|...|..:..|...|:|:|:|..      :.|..|..::|    ..
Human    40 EGNTVPGEWPWQASV-RRQGAHICSGSLVADTWVLTAAHCFE------KAAATELNSWSVVLGSL 97

  Fly   106 DRENYA------DIDTIQFPEKFIYQKLYMDVAVVRLRDPV------------------------ 140
            .||..:      .:..:|.|..:.:.....|:|:::|..|.
Human    98 QREGLSPGAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTTHTPLCLPQPAHRFPFGASCWATG 162

  Fly   141 ------------RGRLTEFIRLCSVKVQ------------PKMQMVVFGWGFDNTEVEIPSSDP- 180
                        |.:|.|.:.|.||.|.            |:.|          |....||..|
Human   163 WDQDTSDGKCWPRLKLGEALCLPSVTVSAPNCPGFQSPLLPRSQ----------TLAPAPSLSPA 217

  Fly   181 ----RNVTVTIISIKEC-------RQKFKSPKIASTSIC-ARQPKNPKQCLYDGGSPLIYGRELC 233
                ||:.:.:||...|       .|:..|.......:| ..||.....|..|.|.|:     ||
Human   218 PGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPV-----LC 277

  Fly   234 ----------GVVSFGSHCIDTSRPGMYTNI--------RRVK--RFITETEESINAGD 272
                      |::||.|.|.....|.:.||.        .||:  .|:.::.|:....|
Human   278 LEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHSSWLQARVQGAAFLAQSPETPEMSD 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34129	NP_001036760.1	Tryp_SPc	39..261	CDD:214473	61/306 (20%)
CG34129	NP_001036760.1	Tryp_SPc	55..261	CDD:304450	58/296 (20%)
PRSS53	XP_011544118.1	Tryp_SPc	42..316	CDD:238113	59/295 (20%)
		Tryp_SPc	43..314	CDD:214473	58/292 (20%)
		Tryp_SPc	359..>512	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100