DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34129 and Prss53

DIOPT Version :9

Sequence 1:	NP_001036760.1	Gene:	CG34129 / 43181	FlyBaseID:	FBgn0083965	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	NP_001074737.1	Gene:	Prss53 / 330657	MGIID:	2652890	Length:	552	Species:	Mus musculus

Alignment Length:	299	Identity:	66/299 - (22%)
Similarity:	115/299 - (38%)	Gaps:	69/299 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGLSKIWLLVSCLLWTCLPQSQGTVYPRDILLKTPKFRRV--------WGGVQSNTGPNFGG--- 54
            |.:...||             |..|:....|::.|...::        .|.::| .||..|.
Mouse   261 MAVHSSWL-------------QAHVHEAAFLVQAPGVVKMSDENSCVACGSLRS-AGPQAGALSQ 311

  Fly    55 --WLLRILNGDGNFACGAAYYAPLLVITSANCIYPYRNSLEGATVEGTAFSECDRENYADIDTIQ 117
              |..| |...|..|||.|..:.::|:|:|:| :..|.:||..:| |....
Mouse   312 WPWDAR-LKHHGKLACGGALVSEVVVLTAAHC-FIGRQTLEEWSV-GLGAG-------------- 359

  Fly   118 FPEKFIYQKLYM-----------DVAVVRLRDPVRGRLTEFIR-LCSVKVQPKMQMVVFGWGFDN 170
             ||::..::|.:           |||.:.|..||  .|...:| ||.......:.....||....
Mouse   360 -PEEWGLKQLILHGAYTHPEGGYDVAFLLLAQPV--TLGPGLRPLCLPYADHHLPDGEHGWVLGL 421

  Fly   171 TEVEIPSSDPRNVTVTIISIKECRQKFKSP-----KIASTSICARQPKNPKQCLYDGGSPLIYGR 230
            |: :...:.|:.|.||::....|.::..:|     .|....:|......|..|....|:||::..
Mouse   422 TQ-KAGINYPQTVPVTVLGPMACSRQHAAPGGTGIPILPGMVCTTVVGEPPHCEGLSGAPLVHEI 485

  Fly   231 E----LCGVVSFGSHCIDTSRPGMYTNIRRVKRFITETE 265
            .    |.|:.|||..|..:::|.::..:...:.:|:..:
Mouse   486 RGTWFLVGLHSFGDTCQSSAKPAVFAALSAYEDWISNLD 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34129	NP_001036760.1	Tryp_SPc	39..261	CDD:214473	58/255 (23%)
CG34129	NP_001036760.1	Tryp_SPc	55..261	CDD:304450	53/226 (23%)
Prss53	NP_001074737.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..46
		Tryp_SPc	45..271	CDD:238113	4/22 (18%)
		Tryp_SPc	311..522	CDD:238113	54/231 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100