DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34129 and Tmprss13

DIOPT Version :9

Sequence 1:	NP_001036760.1	Gene:	CG34129 / 43181	FlyBaseID:	FBgn0083965	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	XP_006510195.1	Gene:	Tmprss13 / 214531	MGIID:	2682935	Length:	561	Species:	Mus musculus

Alignment Length:	269	Identity:	66/269 - (24%)
Similarity:	105/269 - (39%)	Gaps:	70/269 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 GVQSNTGPNFGG---------WLLRILNGDGNFACGAAYYAPLLVITSANCIYPYRNS-LEGATV 97
            |:::.||...||         |.:.:..|..:. ||........|:|:|:|.:..|.. |||..|
Mouse   312 GLRAMTGRIVGGALTSESKWPWQVSLHFGTTHI-CGGTLIDAQWVLTAAHCFFVTREKLLEGWKV 375

  Fly    98 EGTAFSECDRENYADIDTI-QFPEKFIYQKLYM-----------DVAVVRLRDPVRGRLTEFIRL 150
                        ||....: |.||.....::.:           |:|::||..|:         .
Mouse   376 ------------YAGTSNLHQLPEAASISQIIINGNYTDEQDDYDIALIRLSKPL---------T 419

  Fly   151 CSVKVQP---KMQMVVFG-----W--GFDNTEVEIPSSDP--RNVTVTIISIKECR-----QKFK 198
            .|..:.|   .|....||     |  ||..|:.....:.|  |.|.|.:|..|:|.     ..:.
Mouse   420 LSAHIHPACLPMHGQTFGLNETCWITGFGKTKETDEKTSPFLREVQVNLIDFKKCNDYLVYDSYL 484

  Fly   199 SPKIASTSICARQPKNPK-QCLYDGGSPLIYGRE----LCGVVSFGSHCIDTSRPGMYTNIRRVK 258
            :|::    :||...:..: .|..|.|.||:..:.    |.||.|:|:.|...::||:||.:..|.
Mouse   485 TPRM----MCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQKNKPGVYTKVTEVL 545

  Fly   259 RFITETEES 267
            .:|....||
Mouse   546 PWIYRKMES 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34129	NP_001036760.1	Tryp_SPc	39..261	CDD:214473	63/261 (24%)
CG34129	NP_001036760.1	Tryp_SPc	55..261	CDD:304450	58/240 (24%)
Tmprss13	XP_006510195.1	PHA03378	<6..>122	CDD:223065
		LDLa	<204..220	CDD:238060
		SRCR_2	225..314	CDD:373897	1/1 (100%)
		Tryp_SPc	319..548	CDD:214473	60/254 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910