DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34129 and SCRASP1

DIOPT Version :9

Sequence 1:	NP_001036760.1	Gene:	CG34129 / 43181	FlyBaseID:	FBgn0083965	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	XP_315638.3	Gene:	SCRASP1 / 1276311	VectorBaseID:	AGAP005625	Length:	1322	Species:	Anopheles gambiae

Alignment Length:	236	Identity:	59/236 - (25%)
Similarity:	94/236 - (39%)	Gaps:	59/236 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 CGAAYYAPLLVITSANCI--YP---------------YRNSLEGATVEGTAFSECDRENYADIDT 115
            |||.......|:|:|:|:  ||               |.|:.....:|.|...|..||.:
Mosquito  1104 CGAVLITRYHVLTAAHCLIGYPKSTYRVRIGDYHTAAYDNAELDIFIENTYIHEQFREGH----- 1163

  Fly   116 IQFPEKFIYQKLYMDVAVVRLRDPVRGRLTEFIR-LC----SVKVQPKMQMVVFGWGFDNTEVEI 175
                      .:..|:|||.|:.||  |..:::: :|    .....|.....:.|||......:.
Mosquito  1164 ----------HMSNDIAVVVLKTPV--RFNDYVQPICLPARDAPYLPGQNCTISGWGATEAGSKD 1216

  Fly   176 PSSDPRNVTVTIISIKECRQKFKSPKIASTSI-----CA--RQPKNPKQCLYDGGSPLIYGRE-- 231
            .|.|.|..||.::....||:    |::...|:     ||  .:| ....|..|.|.||:....
Mosquito  1217 SSYDLRAGTVPLLPDSVCRR----PEVYGDSLIDGMFCAGTLEP-GVDSCDGDSGGPLVCPNSEG 1276

  Fly   232 ---LCGVVSFGSHCIDTSRPGMYTNIRRVKRFITETEESIN 269
               |.|:||:|.||...::||:|..:...:.:|   |:.:|
Mosquito  1277 LHTLTGIVSWGKHCGYANKPGVYLKVAHYRDWI---EQKLN 1314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34129	NP_001036760.1	Tryp_SPc	39..261	CDD:214473	56/226 (25%)
CG34129	NP_001036760.1	Tryp_SPc	55..261	CDD:304450	56/226 (25%)
SCRASP1	XP_315638.3	ChtBD2	181..228	CDD:214696
		ChtBD2	289..334	CDD:214696
		LDLa	731..762	CDD:238060
		SRCR	776..878	CDD:278931
		SR	776..877	CDD:214555
		LDLa	884..921	CDD:238060
		SR	927..1025	CDD:214555
		SRCR	932..1025	CDD:278931
		Tryp_SPc	1078..1309	CDD:214473	56/226 (25%)
		Tryp_SPc	1079..1312	CDD:238113	58/232 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910