DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34129 and Cfi

DIOPT Version :9

Sequence 1:	NP_001036760.1	Gene:	CG34129 / 43181	FlyBaseID:	FBgn0083965	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	NP_031712.2	Gene:	Cfi / 12630	MGIID:	105937	Length:	603	Species:	Mus musculus

Alignment Length:	242	Identity:	57/242 - (23%)
Similarity:	94/242 - (38%)	Gaps:	43/242 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 RRVWGGVQSNTG--PNFGGWLLRILNGDGNFACGAAYYAPLLVITSANCIYPYR-NSLEGATVEG 99
            :||.||..:|.|  |    |.:.|.:|. ...||..|.....::|:|:|:.|.| :|.:    ..
Mouse   359 KRVIGGKPANVGDYP----WQVAIKDGQ-RITCGGIYIGGCWILTAAHCVRPSRAHSYQ----VW 414

  Fly   100 TAFSECDREN-YADIDTIQ---FPEKFIYQKLYMDVAVVRLR---DPVRGRLTEFIRLC----SV 153
            ||..:..:.| ...|.|::   ..||:.......|:|::.::   ......|...:..|    ..
Mouse   415 TALLDWLKPNSQLGIQTVKRVIVHEKYNGATFQNDIALIEMKMHTGKKECELPNSVPACVPWSPY 479

  Fly   154 KVQPKMQMVVFGWGFDNTEVEIPSSDPRNVTVTIISIKECRQKFKSPKIASTSICA-RQPKNPKQ 217
            ..||..:.::.|||......::.|.....|.:    |..|.|.:..........|| .:..:...
Mouse   480 LFQPNDRCIISGWGRGKDNQKVYSLRWGEVDL----IGNCSQFYPDRYYEKEMQCAGTRDGSIDA 540

  Fly   218 CLYDGGSPLIYGRELC----------GVVSFGSHCIDTSRPGMYTNI 254
            |..|.|.||:     |          |:||:|.:|.....||:||.:
Mouse   541 CKGDSGGPLV-----CEDINNVTYVWGIVSWGENCGKPEFPGVYTRV 582

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34129	NP_001036760.1	Tryp_SPc	39..261	CDD:214473	57/241 (24%)
CG34129	NP_001036760.1	Tryp_SPc	55..261	CDD:304450	50/223 (22%)
Cfi	NP_031712.2	FIMAC	46..111	CDD:214493
		SR	117..220	CDD:214555
		SRCR	122..219	CDD:278931
		LDLa	232..261	CDD:238060
		LDLa	264..298	CDD:294076
		Tryp_SPc	360..589	CDD:214473	57/241 (24%)
		Tryp_SPc	361..592	CDD:238113	56/240 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910