DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34129 and tmprss2.12

DIOPT Version :9

Sequence 1:	NP_001036760.1	Gene:	CG34129 / 43181	FlyBaseID:	FBgn0083965	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	XP_031752400.1	Gene:	tmprss2.12 / 100497514	XenbaseID:	XB-GENE-22065925	Length:	497	Species:	Xenopus tropicalis

Alignment Length:	268	Identity:	71/268 - (26%)
Similarity:	106/268 - (39%)	Gaps:	51/268 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 TCLPQSQGTVYPR---DILLKTPKFRRVWGGVQSNTG--PNFGGWLLRILNGDGNFACGAAYYAP 75
            ||   |.|.|...   |..|.|....|:.||..::.|  |    |.:.:...|.|. ||.:..|.
Frog   237 TC---SSGLVVSLKCIDCGLSTYGESRIVGGSSASIGDWP----WQVNLQYDDTNL-CGGSVIAA 293

  Fly    76 LLVITSANCIYPYRNSLEGATVEGT---AF-------SECDRENYADIDTIQFPEKFIYQKLYMD 130
            ..::|:|:|:       :|.|...:   ||       |..|...|: :|.|.....:..|....|
Frog   294 NWIVTAAHCV-------QGDTSSPSLWKAFIGKIKMPSYYDSSAYS-VDRIIVHPDYSSQTNSND 350

  Fly   131 VAVVRLRDPVRGRLTEFIRLCSVKVQPKMQM--------VVFGWGFDNTEVEIPSSDPRNVTVTI 187
            :|:::|:..:     .|..:......|...|        .:.|||..:.:..| ||..:...|.:
Frog   351 IALMKLKTSI-----AFSSISRPVCLPNYGMQWEEGQPCYISGWGTTSQKGSI-SSVLKYAMVPL 409

  Fly   188 ISIKECRQKFK-SPKIASTSICARQPK-NPKQCLYDGGSPLIYGRE----LCGVVSFGSHCIDTS 246
            ||...|.|... :..|.|:.|||..|| ....|..|.|.||:....    |.|..|:|..|.:..
Frog   410 ISPTTCNQTIMYNGAITSSMICAGYPKGGVDSCQGDSGGPLVTKTNSLWWLVGDTSWGDGCANVY 474

  Fly   247 RPGMYTNI 254
            |||:|.|:
Frog   475 RPGVYGNM 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34129	NP_001036760.1	Tryp_SPc	39..261	CDD:214473	63/242 (26%)
CG34129	NP_001036760.1	Tryp_SPc	55..261	CDD:304450	58/224 (26%)
tmprss2.12	XP_031752400.1	LDLa	127..155	CDD:238060
		SRCR_2	160..255	CDD:406055	7/20 (35%)
		Tryp_SPc	261..489	CDD:238113	62/241 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910