DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34129 and f12

DIOPT Version :9

Sequence 1:	NP_001036760.1	Gene:	CG34129 / 43181	FlyBaseID:	FBgn0083965	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	XP_017947702.2	Gene:	f12 / 100493769	XenbaseID:	XB-GENE-1004811	Length:	597	Species:	Xenopus tropicalis

Alignment Length:	251	Identity:	69/251 - (27%)
Similarity:	114/251 - (45%)	Gaps:	45/251 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 KTPKFR-RVWGGVQS--NTGPNFGGWLLRILNGDGNFACGAAYYAPLLVITSANCIYPYRNSLEG 94
            |||... |:.||:.:  .:.|     .:..|..|.:| ||.:..:|..::|:|:|:....|..:.
Frog   351 KTPSIMPRIVGGLVALPASHP-----YIAALYIDNHF-CGGSLISPCWIVTAAHCLDQRPNVTKI 409

  Fly    95 ATVEGTAFSECDRENYADIDTIQ-FPEKFIYQKLYM------DVAVVRLRDPVRG----RLTEFI 148
            :.|.|.:     |.|..|..|:. ..||:|..:.|.      |:|:|:::. :.|    ..::|:
Frog   410 SVVLGQS-----RFNTTDQHTVTLLVEKYILHEKYYGDTLQHDIALVKVKS-INGLCASEFSQFV 468

  Fly   149 RLCSVKVQPKM-----QMVVFGWGFDNTEVEIPSSDPRNVTVTIISIKECRQKFKSPKIAST--- 205
            :...:..|.||     |.||.|||......|..:...:..::.||...:|    :||.:...
Frog   469 QPICLPQQFKMAESTKQCVVAGWGHQYEGAEHYAFFLQEASMPIIPYTQC----QSPSVHGDRML 529

  Fly   206 --SICAR-QPKNPKQCLYDGGSPLIY---GR-ELCGVVSFGSHCIDTSRPGMYTNI 254
              .:||. .......|..|.|.||:.   || ||.||||:||.|.:.::||:||.:
Frog   530 PGMLCAGFMEGGVDACQGDSGGPLVCEVDGRIELHGVVSWGSGCAEENKPGVYTAV 585

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34129	NP_001036760.1	Tryp_SPc	39..261	CDD:214473	66/244 (27%)
CG34129	NP_001036760.1	Tryp_SPc	55..261	CDD:304450	62/226 (27%)
f12	XP_017947702.2	fn2	46..87	CDD:394995
		EGF_CA	95..129	CDD:238011
		KR	213..298	CDD:214527
		Tryp_SPc	359..595	CDD:238113	65/243 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910