DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34129 and tmprss3a

DIOPT Version :9

Sequence 1:	NP_001036760.1	Gene:	CG34129 / 43181	FlyBaseID:	FBgn0083965	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	XP_021334565.1	Gene:	tmprss3a / 100000148	ZFINID:	ZDB-GENE-070912-70	Length:	543	Species:	Danio rerio

Alignment Length:	283	Identity:	66/283 - (23%)
Similarity:	103/283 - (36%)	Gaps:	87/283 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 PKF-RRVWGGVQSNTG--PNFGGWLLRILNGDGNFACGAAYYAPLLVITSANCIYPYRNSLEGAT 96
            ||| .|:.||..|..|  |    |.:. |:......||.:......::|:|:|:|.....:....
Zfish   292 PKFSARIVGGNLSAEGQFP----WQVS-LHFQNEHLCGGSIITSRWILTAAHCVYGIAYPMYWMV 351

  Fly    97 VEG---------TAFSECDRENYADIDTIQFPEKFIYQKLYM------DVAVVRLRDPVR----- 141
            ..|         .||:               .||.||...|.      |:|:::|..|:.
Zfish   352 YAGLTELPLNAVKAFA---------------VEKIIYHSRYRPKGLDHDIALMKLAQPLTFNGMV 401

  Fly   142 --------GRLTEFIRLCSVKVQPKMQMVVFGWGF--DNTEVEIPSSDPRNVTVTIISIKECRQK 196
                    |...|..::|.:.          |||.  |..:..:   .....:|.:||.|.|.|
Zfish   402 EPICLPNFGEQFEDGKMCWIS----------GWGATEDGGDASV---SQHCASVPLISNKACSQ- 452

  Fly   197 FKSPKI-----ASTSICARQ-PKNPKQCLYDGGSPL------IYGRELCGVVSFGSHCIDTSRPG 249
               |::     .:..|||.. ......|..|.|.||      |:  :|.|..|:|..|.:.::||
Zfish   453 ---PEVYQGYLTAGMICAGYLDGGTDSCQGDSGGPLACEDSSIW--KLVGATSWGQGCAEKNKPG 512

  Fly   250 MYTNIRRVKRFI---TETEESIN 269
            :||.|.:...:|   .|.||.::
Zfish   513 VYTRITQSLTWIHLQMEREEILH 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34129	NP_001036760.1	Tryp_SPc	39..261	CDD:214473	59/265 (22%)
CG34129	NP_001036760.1	Tryp_SPc	55..261	CDD:304450	53/247 (21%)
tmprss3a	XP_021334565.1	LDLa	154..186	CDD:238060
		SRCR_2	191..292	CDD:317845	66/283 (23%)
		Tryp_SPc	298..525	CDD:238113	58/265 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910