Protein Alignment CG6073 and HGH1

DIOPT Version :10

• Sequence 1: NP_651468.1
• Gene: CG6073 / 43180
• FlyBaseID: FBgn0039417
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: NP_011703.3
• Gene: HGH1 / 853099
• SGDID: S000003419
• Length: 394
• Species: Saccharomyces cerevisiae
• Alignment Length: 402
• Identity: 105/402 - (26%)
• Similarity: 183/402 - (45%)
• Gaps: 63/402 - (15%)

  Fly     4 VKELVQFMQPNQRLDLKAVALTHVLGLTGSSEGKSAILSLDEM--LMAIFGLTFD---ANQTVAK 63
            :.|||:|:...|.. ::.:|:.:::|.:.....|  :...|..  :..|..:..|   ..:.:.:
Yeast     5 LNELVEFLHSPQPA-VRQIAIDNLVGFSAGPTSK--VFKNDSYRPIKDIIKMIMDPEHGTRVIIQ 66

  Fly    64 DAVLSLINLTSEEEAAIKVFQLAKQLQPPFAIVEVAAKEITNEQSDLADPWSMVLSNLT------ 122
            ..|..|:|| ||::....:.....:....|.:.::.  ::||..:|:   ..::||||.
Yeast    67 QGVTILVNL-SEDKLVRNIILSDDKKFLKFLVWKIV--DLTNPNADI---MCILLSNLAKDDGIL 125

  Fly   123 ------------------RVESLVHEILDTLERDDHTLPRLAKAFAQLDYNKKKAK---LHYLAP 166
                              ::.:|..|:..:|...|..:....|.     |:||..|   .:|||.
Yeast   126 AVLNIKRNSSGEEVDDGLKLAALNKEVFKSLRAMDCLMDCFVKG-----YDKKLTKYASFNYLAF 185

  Fly   167 IFCNLTQVSRGRELCC-HRKYE---LLEKLLPFASFEGSVVRRGGTIGILKNVCFDTVYHDVIL- 226
            .|.::::...||.... .::|:   .:.|||.|.....:.|||.|....:||..||:..|:.:|
Yeast   186 FFADISRFKLGRMYFIEEQEYDGVVPISKLLVFTEKYDAKVRREGVASTIKNSLFDSETHERLLK 250

  Fly   227 NEQSSILVAILQPLCGPE--EFSDEDNELLPIELQYLPESKTREEDPDLRKMLLECLLQLCSTRR 289
            :|:.::|..||.|:...:  |..:||...||.|||.|||.|.|:..|.:....||.:|.||:|..
Yeast   251 DEKINLLPYILLPIASAKDSEIDEEDMFNLPDELQLLPEDKERDPIPAIICCHLESILLLCTTHA 315

  Fly   290 SREILRSRGVYEILREYHKWEAKVGKDSDCLLACENVVDILIKKE------EEIGLDNYKTEVEV 348
            .||.||.:.||.::||.||   .| ::.|....|..:|::|::.|      ||:...|.:.|.|.
Yeast   316 GREYLRDKSVYPLVRELHK---NV-ENEDIGELCYRIVNMLMRGEPGAGAVEEMPSKNAEEEEEE 376

  Fly   349 PAEQSEKFVQED 360
            .:|:.|...:||
Yeast   377 ESEEEEDDDEED 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6073	NP_651468.1	DUF383	103..275	CDD:461153	56/205 (27%)
		DUF384	280..338	CDD:461154	22/63 (35%)
HGH1	NP_011703.3	DUF383	99..301	CDD:461153	56/211 (27%)
		DUF384	306..360	CDD:461154	20/57 (35%)