Protein Alignment CG6073 and HGH1

DIOPT Version :9

• Sequence 1: NP_001247313.1
• Gene: CG6073 / 43180
• FlyBaseID: FBgn0039417
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: NP_011703.3
• Gene: HGH1 / 853099
• SGDID: S000003419
• Length: 394
• Species: Saccharomyces cerevisiae
• Alignment Length: 402
• Identity: 105/402 - (26%)
• Similarity: 183/402 - (45%)
• Gaps: 63/402 - (15%)

  Fly     4 VKELVQFMQPNQRLDLKAVALTHVLGLTGSSEGKSAILSLDEM--LMAIFGLTFD---ANQTVAK 63
            :.|||:|:...|.. ::.:|:.:::|.:.....|  :...|..  :..|..:..|   ..:.:.:
Yeast     5 LNELVEFLHSPQPA-VRQIAIDNLVGFSAGPTSK--VFKNDSYRPIKDIIKMIMDPEHGTRVIIQ 66

  Fly    64 DAVLSLINLTSEEEAAIKVFQLAKQLQPPFAIVEVAAKEITNEQSDLADPWSMVLSNLT------ 122
            ..|..|:|| ||::....:.....:....|.:.::.  ::||..:|:   ..::||||.
Yeast    67 QGVTILVNL-SEDKLVRNIILSDDKKFLKFLVWKIV--DLTNPNADI---MCILLSNLAKDDGIL 125

  Fly   123 ------------------RVESLVHEILDTLERDDHTLPRLAKAFAQLDYNKKKAK---LHYLAP 166
                              ::.:|..|:..:|...|..:....|.     |:||..|   .:|||.
Yeast   126 AVLNIKRNSSGEEVDDGLKLAALNKEVFKSLRAMDCLMDCFVKG-----YDKKLTKYASFNYLAF 185

  Fly   167 IFCNLTQVSRGRELCC-HRKYE---LLEKLLPFASFEGSVVRRGGTIGILKNVCFDTVYHDVIL- 226
            .|.::::...||.... .::|:   .:.|||.|.....:.|||.|....:||..||:..|:.:|
Yeast   186 FFADISRFKLGRMYFIEEQEYDGVVPISKLLVFTEKYDAKVRREGVASTIKNSLFDSETHERLLK 250

  Fly   227 NEQSSILVAILQPLCGPE--EFSDEDNELLPIELQYLPESKTREEDPDLRKMLLECLLQLCSTRR 289
            :|:.::|..||.|:...:  |..:||...||.|||.|||.|.|:..|.:....||.:|.||:|..
Yeast   251 DEKINLLPYILLPIASAKDSEIDEEDMFNLPDELQLLPEDKERDPIPAIICCHLESILLLCTTHA 315

  Fly   290 SREILRSRGVYEILREYHKWEAKVGKDSDCLLACENVVDILIKKE------EEIGLDNYKTEVEV 348
            .||.||.:.||.::||.||   .| ::.|....|..:|::|::.|      ||:...|.:.|.|.
Yeast   316 GREYLRDKSVYPLVRELHK---NV-ENEDIGELCYRIVNMLMRGEPGAGAVEEMPSKNAEEEEEE 376

  Fly   349 PAEQSEKFVQED 360
            .:|:.|...:||
Yeast   377 ESEEEEDDDEED 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6073	NP_001247313.1	DUF383	103..275	CDD:281984	56/205 (27%)
		DUF384	280..337	CDD:281985	21/62 (34%)
HGH1	NP_011703.3	DUF383	99..301	CDD:397949	56/211 (27%)
		DUF384	306..360	CDD:397950	20/57 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346544
Domainoid	1	1.000	56	1.000	Domainoid score	I2709
eggNOG	1	0.900	-	-		E1_KOG2973
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H48742
Inparanoid	1	1.050	96	1.000	Inparanoid score	I1502
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54604
OrthoFinder	1	1.000	-	-		FOG0004316
OrthoInspector	1	1.000	-	-		oto100147
orthoMCL	1	0.900	-	-		OOG6_103137
Panther	1	1.100	-	-	LDO	PTHR13387
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R426
SonicParanoid	1	1.000	-	-		X3587
TreeFam	1	0.960	-	-
	15	14.790