DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31086 and CG10916

DIOPT Version :9

Sequence 1:	NP_001247312.1	Gene:	CG31086 / 43179	FlyBaseID:	FBgn0051086	Length:	148	Species:	Drosophila melanogaster
Sequence 2:	NP_001261070.1	Gene:	CG10916 / 37081	FlyBaseID:	FBgn0034312	Length:	263	Species:	Drosophila melanogaster

Alignment Length:	133	Identity:	50/133 - (37%)
Similarity:	78/133 - (58%)	Gaps:	9/133 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 PQAAVVAGHDSDGDTIFIGRAFYCNDMLPAKIIPNKGKAYVAYA------NQEVELENYEVLSGF 73
            |:.||..|.:.||...::.|.:|.:|:|||..:|.|..|:.:::      ..:||:   .||:..
  Fly   124 PEGAVQCGTNEDGLPTYVARGYYHDDLLPAPYVPEKKAAFGSHSCSARTLTDDVEI---LVLNDC 185

  Fly    74 NYEWLPAENGEVPPGAVKVGQNVDGETLYAGRGYHAGSLTVGKVHPSHGCLYIPYDSEEVKIFAY 138
            :|:|:|.::|..|..|:..|.:..||..|.|||.:.|.|.:|||||||..:|||:..:||.:..|
  Fly   186 DYKWVPGQHGTYPRDALNTGYSELGEVTYTGRGLYQGILRLGKVHPSHKVMYIPHHGQEVSVNTY 250

  Fly   139 EVL 141
            |||
  Fly   251 EVL 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31086	NP_001247312.1	DM9	3..73	CDD:128937	19/63 (30%)
		DUF3421	24..134	CDD:288732	41/115 (36%)
		DM9	74..143	CDD:128937	31/68 (46%)
CG10916	NP_001261070.1	zf-RING_2	32..74	CDD:290367
		zf-rbx1	<32..74	CDD:289448
		DM9	105..183	CDD:128937	18/61 (30%)
		DUF3421	133..246	CDD:288732	41/115 (36%)
		DM9	186..254	CDD:128937	31/68 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449324
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005929
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR31649
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940