DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6142 and AT1G14185

DIOPT Version :9

Sequence 1:	NP_651466.1	Gene:	CG6142 / 43178	FlyBaseID:	FBgn0039415	Length:	616	Species:	Drosophila melanogaster
Sequence 2:	NP_563939.1	Gene:	AT1G14185 / 837978	AraportID:	AT1G14185	Length:	503	Species:	Arabidopsis thaliana

Alignment Length:	580	Identity:	148/580 - (25%)
Similarity:	245/580 - (42%)	Gaps:	147/580 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 YDFIIVGAGSAGCVMANRLSEISSASVLLLEAGDQETFISDVPLTAALTQMTRYNWGYKAEPTEH 112
            :|:|:||.|:|||.:|..|||  ..|||::|.|..       |....|.:..:| :||....|:.
plant    37 FDYIVVGGGTAGCSLAATLSE--KYSVLVIERGGS-------PFGDPLVEDKKY-YGYSLINTDE 91

  Fly   113 ---------ACQGLKGGVCNWPKGRGVGGTSLINFMLYTRGHRRDYDEWAAANNSGWSYDELLPY 168
                     :..|:|.     .:||.:||:|.||...|:|..    ||:  ...:||..|.:...
plant    92 YSSVAQSFTSVDGIKN-----HRGRVLGGSSAINGGFYSRAS----DEF--VKKAGWDKDLVQES 145

  Fly   169 FR--KSERIGIPELYKSPYHGRNGQLDVQYTDYRSQLLKAFLKSGREMGYEITDPNGEH-----L 226
            ::  :|:.:.:|||.:.....:.|.|:..:..|....|:.  ..|.::|..|.|..|:.     |
plant   146 YKWVESKVVFMPELTRWQSIVQFGFLEAGFYPYNGYSLEH--TQGTKIGGSIFDQCGKRHTSADL 208

  Fly   227 MGFARSQATIRNGRRCSTSKAFIQPVVNRKNLHISMKSWVTRLIIDPITKTATGVEFV------- 284
            :|:.:.        .|.|               :.:.:.|..:|.|.....|.||.|:
plant   209 LGYGKP--------NCIT---------------VLLNATVKSIIFDANKTRAVGVRFMESDGNSS 250

  Fly   285 KQRQRYVVRARKEVILSAGTIASPQLLMLSGIGPAEHLREHNITVMQDL-PVGYNLQDHITLNGL 348
            |..:.:|.:.|.||||:||.:.|||:|:||||||..||.:.:|.|:.:| .||..:.|:..::.|
plant   251 KSYKVHVEQHRGEVILAAGALGSPQILLLSGIGPENHLNDFDIPVIVNLKEVGKQMSDNPAISLL 315

  Fly   349 V--FVVNDSTVNDARLLNPSDIFRYIFAGQGPYTIPGGAEAFAFVRTPSSKFAKDYPDMELVLGA 411
            |  |..| .||:..:::..::.|::|.                               ..|||..
plant   316 VDRFSQN-LTVDPPQVVAITEGFKFIL-------------------------------QSLVLPT 348

  Fly   412 GSLSGDRFGTMRNLLGITDEFYDYMFGDLQSKETFGLVPVLLRPKSRGRISLRSRNPFHWPRMEP 476
                  ...|.|..:.....|                      |||:||:.|.:.||...|.:..
plant   349 ------NITTTRTAISAKIAF----------------------PKSKGRLKLNNTNPRENPSVTF 385

  Fly   477 NFMQHPDDVRAMIEGIEMILKLSRSKPMA-KMGTRFHDRPFPGCENLKFASEAYWKCCLRRYGSS 540
            |::::..|:.|..|.:..:..::|||.:. .:||:..|:...|.|.||       |.|::.. .:
plant   386 NYLENKADLDACQEMVLHLQHVARSKTVTFFLGTQAQDKLVAGDEELK-------KFCIKNV-RT 442

  Fly   541 LQHQSGTCKMGPATDNTSVVDAQLRIHGIRGLRVVDASVLPNVPAGHTNAIVIMVAEKAG 600
            ..|..|.|.:|      |||:.:.:::|::.|||||.|.....|..:..|.|:|:....|
plant   443 YYHYHGGCVVG------SVVNEEYKVNGVKRLRVVDGSTFEESPGTNPMATVLMLGRYQG 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6142	NP_651466.1	PRK02106	47..604	CDD:235000	148/580 (26%)
		NADB_Rossmann	48..342	CDD:304358	89/317 (28%)
		GMC_oxred_C	455..599	CDD:282984	43/144 (30%)
AT1G14185	NP_563939.1	PRK02106	35..492	CDD:235000	147/574 (26%)
		NAD_binding_8	41..99	CDD:290186	21/67 (31%)
		NADB_Rossmann	109..311	CDD:304358	65/232 (28%)
		GMC_oxred_C	364..492	CDD:282984	43/141 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I3423
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I1608
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D798314at2759
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		mtm950
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.870