Protein Alignment CG6142 and Chdh

DIOPT Version :9

• Sequence 1: NP_651466.1
• Gene: CG6142 / 43178
• FlyBaseID: FBgn0039415
• Length: 616
• Species: Drosophila melanogaster
• Sequence 2: NP_001129712.1
• Gene: Chdh / 218865
• MGIID: 1860776
• Length: 596
• Species: Mus musculus
• Alignment Length: 583
• Identity: 210/583 - (36%)
• Similarity: 297/583 - (50%)
• Gaps: 75/583 - (12%)

  Fly    47 EYDFIIVGAGSAGCVMANRLSEISSASVLLLEAGDQETFISD------VPLTAALTQM---TRYN 102
            ||.|::|||||||||:|:||:|..:..|||||||.::..:..      :.:.|||...   .:||
Mouse    42 EYTFVVVGAGSAGCVLASRLTEDPNHRVLLLEAGPKDLLMGSKRLQWKIHMPAALVSNLCDDKYN 106

  Fly   103 WGYKAEPTEHACQGLKGGVCNWPKGRGVGGTSLINFMLYTRGHRRDYDEWAAANNSGWSYDELLP 167
            |.|..||.    .|:...|..||:||..||:|.:|.|:|.|||..||:.|......||.|...||
Mouse   107 WYYHTEPQ----PGMDSRVLYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWHREGAEGWDYAHCLP 167

  Fly   168 YFRKSERIGIPELYKSPYHGRNGQLDVQYTDYRSQLLKAFLKSGREMGYEIT-DPNGEHLMGFAR 231
            ||||::|   .||..:.|.|.:|.|.|........|.:|||::.|:.||..| |.||....||..
Mouse   168 YFRKAQR---HELGANMYRGGDGPLHVSRGKTNHPLHQAFLQAARQAGYPFTEDMNGFQQEGFGW 229

  Fly   232 SQATIRNGRRCSTSKAFIQPVVNRKNLHISMKSWVTRLIIDPITKTATGVEFVKQRQRYVVRARK 296
            ...|:..|:|.||:.|::.||::|.||...:::.|:|::.:  ...|.|||::|..||:.....:
Mouse   230 MDMTVHQGKRWSTACAYLHPVLSRPNLRAEVQTLVSRVLFE--GTRAVGVEYIKDGQRHKAYVSR 292

  Fly   297 EVILSAGTIASPQLLMLSGIGPAEHLREHNITVMQDLP-VGYNLQDHITLNGLVFVVNDSTVNDA 360
            |||||.|.|.|||||||||:|.|:.||:.:|.|:..|| ||.|||||:.:     .|..:.....
Mouse   293 EVILSGGAINSPQLLMLSGVGNADDLRKLDIPVVCHLPGVGQNLQDHLEV-----YVQQACTQPI 352

  Fly   361 RLLNPSDIFRYIFAG---QGPYTIPGGA---EAFAFVRTPSSKFAKDYPDMEL-VLGAGSLSGDR 418
            .|.:.....|.:..|   ...||..|..   |...|:|   |:....:||::. .|.:..:...|
Mouse   353 TLHSAQKPLRKVCIGLEWLWSYTGDGATAHLETGGFIR---SRPGVPHPDIQFHFLPSQVIDHGR 414

  Fly   419 FGTMRNLLGITDEFYDYMFGDLQSKETFGLVPVLLRPKSRGRISLRSRNPFHWPRMEPNFMQHPD 483
            ..|.:       |.|....|             .:|..|.|.:.|||.||...|.:.||::....
Mouse   415 KPTQQ-------EAYQVHVG-------------TMRATSVGWLKLRSANPRDHPVIHPNYLSTET 459

  Fly   484 DVRAMIEGIEMILKLSR----SKPMAKMGTRFHDRPFPGCE---NLKFASEAYWKCCLRRYGSSL 541
            ||    |.....::|||    .:.:|         ||.|.|   .....|:......:|....|.
Mouse   460 DV----EDFRQCVRLSREIFAQEALA---------PFRGKELQPGSHVQSDKEIDAFVRAKADSA 511

  Fly   542 QHQSGTCKMGPATDNTSVVDAQLRIHGIRGLRVVDASVLPNVPAGHTNAIVIMVAEKAGDMIK 604
            .|.|.|||||.::|.|:|||||.::.|:..|||||||::|:|.:|:.||..:|:||||.|:||
Mouse   512 YHPSCTCKMGRSSDPTAVVDAQTKVIGVENLRVVDASIMPSVVSGNLNAPTVMIAEKAADIIK 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6142	NP_651466.1	PRK02106	47..604	CDD:235000	208/581 (36%)
		NADB_Rossmann	48..342	CDD:304358	128/304 (42%)
		GMC_oxred_C	455..599	CDD:282984	54/150 (36%)
Chdh	NP_001129712.1	PRK02106	42..588	CDD:235000	210/583 (36%)
		NAD_binding_8	47..>76	CDD:290186	19/28 (68%)
		GMC_oxred_N	118..341	CDD:279121	98/227 (43%)
		GMC_oxred_C	432..569	CDD:282984	54/149 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	241	1.000	Domainoid score	I2232
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	336	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52181
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		otm42468
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.870