Protein Alignment CG6142 and chdh

DIOPT Version :9

• Sequence 1: NP_651466.1
• Gene: CG6142 / 43178
• FlyBaseID: FBgn0039415
• Length: 616
• Species: Drosophila melanogaster
• Sequence 2: XP_002663301.2
• Gene: chdh / 100331020
• ZFINID: ZDB-GENE-120111-1
• Length: 585
• Species: Danio rerio
• Alignment Length: 588
• Identity: 209/588 - (35%)
• Similarity: 301/588 - (51%)
• Gaps: 83/588 - (14%)

  Fly    46 PEYDFIIVGAGSAGCVMANRLSEISSASVLLLEAGDQETFISDVPLT------AALTQM---TRY 101
            |.|.::||||||||||:|:||:|..|.||||||||.::..:....|:      ||||..   .||
Zfish    33 PSYSYVIVGAGSAGCVLASRLTENPSDSVLLLEAGPKDKHLGSTRLSWKIHMPAALTYNLCDDRY 97

  Fly   102 NWGYKAEPTEHACQGLKGGVCNWPKGRGVGGTSLINFMLYTRGHRRDYDEWAAANNSGWSYDELL 166
            ||.|...|..|    :...|..||:||..||:|.:|.|:|.|||..||:.|.:....||:||..|
Zfish    98 NWFYHTLPQAH----MDDRVMYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWQSEGADGWNYDHCL 158

  Fly   167 PYFRKSERIGIPELYKSPYHGRNGQLDVQYTDYRSQLLKAFLKSGREMGYEIT-DPNGEHLMGFA 230
            |||||::   ..||....|.|.:|.|.|.....::.|..||:::|::.||..| |.||....|..
Zfish   159 PYFRKAQ---THELGPDRYRGGDGPLHVSRGKTQNPLHYAFIQAGQQAGYPYTEDMNGFQQEGVG 220

  Fly   231 RSQATIRNGRRCSTSKAFIQPVVNRKNLHISMKSWVTRLIIDPITKTATGVEFVKQRQRYVVRAR 295
            ....||..|:|.||:.|:::|.::|.||...::..|||::.|  ...|.|||:.:..|...|.|.
Zfish   221 WMDMTIHKGQRWSTASAYLRPALSRPNLSTEVRCMVTRVLFD--GARARGVEYQQNGQIKKVFAE 283

  Fly   296 KEVILSAGTIASPQLLMLSGIGPAEHLREHNITVMQDLP-VGYNLQDHITLNGLVFVVNDSTVND 359
            ||||||.|.|.|||||:|||:|.|:.|:..:|.|:|.|| ||.|||||:.|    :|.:..|
Zfish   284 KEVILSGGAINSPQLLLLSGVGNADELKTLDIPVVQHLPGVGCNLQDHLEL----YVQHACT--- 341

  Fly   360 ARLLNPSDIFRYIFAGQGP----------------YTIPGGAEAFAFVRTPSSKFAKDYPDMELV 408
                .|..::|    .|.|                |......|:..|:|   |:....:||::..
Zfish   342 ----QPITLYR----AQKPLQMLKIGLEWLLKFTGYGATAHLESGGFIR---SRPDVPHPDIQFH 395

  Fly   409 LGAGSLSGDRFGTMRNLLGITDEFYDYMFGDLQSK-ETFGLVPVLLRPKSRGRISLRSRNPFHWP 472
            .                  :..:..|:  |.:.|| |.|.:....:|..|.|.:.|:|::|...|
Zfish   396 F------------------LPSQVIDH--GRVSSKIEAFQVHVGPMRSTSVGWLKLKSKDPRDHP 440

  Fly   473 RMEPNFMQHPDDVRAMIEGIEMILKLSRSKPMAKM-GTRFHDRPFPGCENLKFASEAYWKCCLRR 536
            .::||::....||....|.:.:..::...:...:. |...  :|.|..:     |:|.....:|:
Zfish   441 ILQPNYLSTETDVLEFRECVRLTREIFAQQAFDEFRGPEV--QPGPAVQ-----SDAEIDAFVRQ 498

  Fly   537 YGSSLQHQSGTCKMGPATDNTSVVDAQLRIHGIRGLRVVDASVLPNVPAGHTNAIVIMVAEKAGD 601
            ...|..|.|.|||||...|..:||..:||:.|:.|||||||||:|::.:|:.||..||:||||.|
Zfish   499 KADSAYHPSCTCKMGRPEDRMAVVSPELRVFGVEGLRVVDASVMPSMVSGNLNAPTIMIAEKAAD 563

  Fly   602 MIK 604
            .||
Zfish   564 AIK 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6142	NP_651466.1	PRK02106	47..604	CDD:235000	206/585 (35%)
		NADB_Rossmann	48..342	CDD:304358	132/304 (43%)
		GMC_oxred_C	455..599	CDD:282984	48/144 (33%)
chdh	XP_002663301.2	PRK02106	30..585	CDD:235000	209/588 (36%)
		NADB_Rossmann	38..>69	CDD:304358	23/30 (77%)
		GMC_oxred_N	110..333	CDD:279121	98/227 (43%)
		GMC_oxred_C	424..561	CDD:282984	48/143 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	241	1.000	Domainoid score	I2198
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	342	1.000	Inparanoid score	I2314
OMA	1	1.010	-	-		QHG52181
OrthoDB	1	1.010	-	-		D173099at33208
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		otm24368
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.980