DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14544 and cpd1

DIOPT Version :9

Sequence 1:	NP_001303484.1	Gene:	CG14544 / 43170	FlyBaseID:	FBgn0039407	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_593567.1	Gene:	cpd1 / 2542192	PomBaseID:	SPAC9G1.12	Length:	364	Species:	Schizosaccharomyces pombe

Alignment Length:	377	Identity:	119/377 - (31%)
Similarity:	172/377 - (45%)	Gaps:	81/377 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSFLKPKTHIEKGDVVILYLSVSSMHAIEAVPEIVNKKGETIP-HI-----FQTNYGSLKVENII 59
            |.|...|..:|.||:.:.::.                :.:.|| ||     |...||:.....:|
pombe     1 MVFADYKQRVENGDLAVAWIG----------------RNKLIPLHIEAEKTFHNQYGAFPHSEMI 49

  Fly    60 GVEYGSKV--ELSKGWAHVLQPTPELWTQTLPHRTQIIYTPDISMIIHQLEVRPGAVVVESGTGS 122
            |..||.::  ...:|:.::|||||||||..|||||||:|||||::|..:|.:..|..|:|:||||
pombe    50 GKRYGEQIASTAKQGFIYLLQPTPELWTLALPHRTQIVYTPDIALIHQKLRITYGTRVIEAGTGS 114

  Fly   123 GSLSHYFLRALKPTGHLHTFDFHEARADQARDEFRRH----GIADFVTVYHRDVCNLGFGAELDG 183
            .|:||...|.:.|.|.|.||::|..|...|..|||.|    .:.....:.|||||..|| .:.:.
pombe   115 ASMSHAISRTVGPLGRLFTFEYHATRYQTALQEFREHEMLIDVGGNTHLTHRDVCKDGF-LDTEV 178

  Fly   184 KADAVFLDLPAPDLAVPHAFKALKL-SGGRFCSFSPCIEQSQRCIQELTKLGFNEIVSLEVLQQE 247
            |.||:|||||||..|:||....:.. ...|.|.|||||||.|...:.|.:||:.:|..:||..::
pombe   179 KVDAIFLDLPAPWEAIPHLSNHVNHDKSTRICCFSPCIEQIQHSAEALRELGWCDIEMIEVDYKQ 243

  Fly   248 NVVKTRTLPVID--LEFLK-----------------------------------LPKTDETTAAT 275
            ...:...:..||  ::.||                                   |.:...:.:..
pombe   244 WAARKSRIVHIDEAIDRLKEVKRRRIEGFERRKMRREQNLSSDAKVEDQDNDSMLGENKSSVSTE 308

  Fly   276 NALESKAPKEVKK----------YLTSSNPQTLPGHTGFLTFAT-LPPNIPK 316
            .||:....|.:::          ....||   |..||.:|.||. ||..:.|
pombe   309 TALKPVTNKRIREGDGNYEWTDVARVDSN---LKSHTSYLLFAVHLPSQLDK 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14544	NP_001303484.1	GCD14	72..310	CDD:285866	99/290 (34%)
cpd1	NP_593567.1	Gcd14	9..274	CDD:225317	101/281 (36%)
cpd1	NP_593567.1	GCD14	64..350	CDD:285866	99/289 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	158	1.000	Domainoid score	I1027
eggNOG	1	0.900	-	-		E1_COG2519
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6229
Inparanoid	1	1.050	172	1.000	Inparanoid score	I1176
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004932
OrthoInspector	1	1.000	-	-		oto101125
orthoMCL	1	0.900	-	-		OOG6_100880
Panther	1	1.100	-	-	LDO	PTHR12133
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1550
SonicParanoid	1	1.000	-	-		X3473
TreeFam	1	0.960	-	-
	13	12.850