Protein Alignment Sld5 and Gins4

DIOPT Version :10

• Sequence 1: NP_651457.1
• Gene: Sld5 / 43166
• FlyBaseID: FBgn0039403
• Length: 228
• Species: Drosophila melanogaster
• Sequence 2: NP_077202.1
• Gene: Gins4 / 109145
• MGIID: 1923847
• Length: 223
• Species: Mus musculus
• Alignment Length: 221
• Identity: 83/221 - (37%)
• Similarity: 137/221 - (61%)
• Gaps: 7/221 - (3%)

  Fly    15 DVSDGAGLEDEDDDDMEQITAQKVLEIIETAWINEMCAPEILPSQTDMLELMVSQVAHMEEQMRD 79
            :|.|..|.:.:...:...:|..:::|.:|.||:||..|||:|.|:.:::|.::.|:.||||.:|.
Mouse     3 EVLDLHGQDSDGGSEEMVLTPAELIEKLEQAWMNEKFAPELLESKAEIVECVMEQLEHMEENLRR 67

  Fly    80 LDKNDFRAVVHSMELERVRYIMASYLRCRLQKIETFTQHILNQEESR-EPDDKRLSPEETKFAQE 143
            ..|.|.:..:|.||:||:||:::|||||||.|||.|..|||.:|:.| |.:...|||||..||:|
Mouse    68 AKKGDLKVSIHRMEMERIRYVLSSYLRCRLMKIEKFFPHILEKEKVRSEGEPSSLSPEEFVFAKE 132

  Fly   144 FASNVDEYFHKVATQYM-PNQQRGEAEQRIVTPNLMSHVFLKANVAVPAVIVGVDDEE-----VD 202
            :..:.:.:|..||.::| ||.|:.:..:.:..|:|.|:|||:.......::|..:.:|     :|
Mouse   133 YMDHTETHFKNVALKHMPPNLQKVDLLRAVPKPDLDSYVFLRVKERQENILVEPEADEQRDYVID 197

  Fly   203 MAAGSQHIIPYQLVADLIQNNQAQLI 228
            :..||||:|.|:.:|.|:.:...|||
Mouse   198 LEVGSQHLIRYKTIAPLVASGAVQLI 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sld5	NP_651457.1	GINS_A_Sld5	38..156	CDD:212549	53/118 (45%)
		GINS_B_Sld5	175..228	CDD:412028	18/57 (32%)
Gins4	NP_077202.1	GINS_A_Sld5	26..146	CDD:212549	54/119 (45%)
		GINS_B_Sld5	165..223	CDD:412028	18/57 (32%)
		Important for GINS complex assembly. /evidence=ECO:0000250	166..223		17/56 (30%)