DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dak1 and URA6

DIOPT Version :9

Sequence 1:	NP_651456.1	Gene:	Dak1 / 43165	FlyBaseID:	FBgn0028833	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_012901.3	Gene:	URA6 / 853844	SGDID:	S000001507	Length:	204	Species:	Saccharomyces cerevisiae

Alignment Length:	205	Identity:	92/205 - (44%)
Similarity:	140/205 - (68%)	Gaps:	11/205 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 ITTTSTAPPHNIGIMSVEKPKIVFVLGGPGAGKGTQCSRIVDRFQFTHLSAGDLLREERSREGSE 108
            :|..:|:.|    ..|.::..::||||||||||||||.::|..:.|.|||||||||.|:.|.||:
Yeast     1 MTAATTSQP----AFSPDQVSVIFVLGGPGAGKGTQCEKLVKDYSFVHLSAGDLLRAEQGRAGSQ 61

  Fly   109 FGNLIEDYIRNGKIVPVEVTCSLLENAMK---ASGKSRFLIDGFPRNQDNLDGWNRQMSEKVDFQ 170
            :|.||::.|:.|:|||.|:|.:||.||:.   .:.|.:||||||||..|....:.|.:   |:.:
Yeast    62 YGELIKNCIKEGQIVPQEITLALLRNAISDNVKANKHKFLIDGFPRKMDQAISFERDI---VESK 123

  Fly   171 FVLFFDCGEDVCVKRCLGRGQSGSGRTDDNLDSLKKRISTYNNDSLPIIKFFEGAGQVKRIDASP 235
            |:|||||.||:.::|.|.||:: |||:|||::|:|||.:|:...|:|:|::||...:|.|:....
Yeast   124 FILFFDCPEDIMLERLLERGKT-SGRSDDNIESIKKRFNTFKETSMPVIEYFETKSKVVRVRCDR 187

  Fly   236 DAEEVFGEVE 245
            ..|:|:.:|:
Yeast   188 SVEDVYKDVQ 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dak1	NP_651456.1	UMP_CMP_kin_fam	65..249	CDD:273576	88/184 (48%)
Dak1	NP_651456.1	ADK	65..240	CDD:238713	86/177 (49%)
URA6	NP_012901.3	UMP_CMP_kin_fam	18..196	CDD:273576	87/181 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	169	1.000	Domainoid score	I788
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32308
Inparanoid	1	1.050	185	1.000	Inparanoid score	I938
Isobase	1	0.950	-	0	Normalized mean entropy	S511
OMA	1	1.010	-	-		QHG54223
OrthoFinder	1	1.000	-	-		FOG0002780
OrthoInspector	1	1.000	-	-		oto99531
orthoMCL	1	0.900	-	-		OOG6_100591
Panther	1	1.100	-	-	LDO	PTHR23359
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1604
SonicParanoid	1	1.000	-	-		X1636
TreeFam	1	0.960	-	-
	15	14.810