DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dak1 and Ak9

DIOPT Version :9

Sequence 1:	NP_651456.1	Gene:	Dak1 / 43165	FlyBaseID:	FBgn0028833	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001357742.1	Gene:	Ak9 / 633979	MGIID:	2685080	Length:	1879	Species:	Mus musculus

Alignment Length:	196	Identity:	40/196 - (20%)
Similarity:	84/196 - (42%)	Gaps:	24/196 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 VEKPKIVFVLGGPGAGKGTQCSRIVDRFQFTHLSAGDLLREERSREGSEFGNLIEDYIRNGKIVP 124
            :.||....:.|.|||||.|....|...::...:.|..:|.|..:.| .|.|.:::..:.:|..:|
Mouse    28 LSKPTCFIIFGKPGAGKTTLARNIAQAWKCIRVEALSVLEEHIAAE-KETGAMLQSLLVSGHSIP 91

  Fly   125 VEVTCSLLENAMKASGKSRF--LIDGFPR-NQDNLDGWNR-QMSEKVDFQ--FVLFFDCGE-DVC 182
            .|:...|:...:|:...:.|  ::...|. .|||:....: ::.:.::.|  .::...|.: |:|
Mouse    92 DELVTKLILEKIKSPEVAHFGYILTEMPSLAQDNMTSLKQIELVKNLELQPDIIINIKCSDYDLC 156

  Fly   183 VKRCLGRGQSGSGRT-------DDNLDSLKKRISTYNNDSLPIIKFFEGAGQVKRIDASPDAEEV 240
            .:.|..|..|.:|..       .:.::|.:::...:..         ||..:.:..:...:.||.
Mouse   157 QRTCGQRQHSTTGYVYTREQWDPEIIESRRRKKRDFPK---------EGKSEEEEEEEEQEEEEA 212

  Fly   241 F 241
            |
Mouse   213 F 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dak1	NP_651456.1	UMP_CMP_kin_fam	65..249	CDD:273576	38/191 (20%)
Dak1	NP_651456.1	ADK	65..240	CDD:238713	36/188 (19%)
Ak9	NP_001357742.1	adk	34..286	CDD:273569	38/190 (20%)
		Ribosomal_L24e_L24	<926..956	CDD:382277
		ADK	962..1177	CDD:238713
		ADK	1381..1553	CDD:238713
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900