DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dak1 and ak7b

DIOPT Version :9

Sequence 1:	NP_651456.1	Gene:	Dak1 / 43165	FlyBaseID:	FBgn0028833	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001103168.2	Gene:	ak7b / 504040	ZFINID:	ZDB-GENE-050309-170	Length:	699	Species:	Danio rerio

Alignment Length:	220	Identity:	37/220 - (16%)
Similarity:	84/220 - (38%)	Gaps:	47/220 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 VLGGPGAGKGTQCSRIVDRFQFTHLSAGDLLR--------------EERSREGSE--FGNLIEDY 116
            ::|.|..||.|...:|...:...|:...:.:.              ||..::..:  :..|.|:.
Zfish   366 IVGPPAVGKSTIAEKICKHYNLHHIKLKEAIAEALENLELCVRTEDEENDQDDDQEFWDTLRENM 430

  Fly   117 IRNGKIVPVEVTCSLLENAM--KASGKSRFLIDGFPRNQDNL------DGWNRQM----SEKVDF 169
            ..||..:..:....::::.:  |......|::||||:..:..      ||....:    :.|:..
Zfish   431 NENGGRLDDQYVIRIMKDKLRTKPCMNQGFVLDGFPKTCEQAKELFTGDGEPEDLESKHATKIIP 495

  Fly   170 QFVLFFDCGEDVCVKRCLGRGQSGSGRTDDNLDSLKKRISTYNN----DSLPIIKFFEGAGQVKR 230
            :||...:..:|....|.|...::....|....:...:|::.:.:    |.:| :.:||.
Zfish   496 EFVFSVNATDDFLKNRVLNLPETVVEGTSYMPEQFLQRLARFRDRNVEDEMP-LNYFED------ 553

  Fly   231 IDASPDAEEVFGE--------VEKI 247
            ::..|:..|:..:        ::||
Zfish   554 LEIHPEHLEITSDNDNEYQLIIDKI 578

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dak1	NP_651456.1	UMP_CMP_kin_fam	65..249	CDD:273576	37/220 (17%)
Dak1	NP_651456.1	ADK	65..240	CDD:238713	34/203 (17%)
ak7b	NP_001103168.2	WcaG	<129..>286	CDD:223528
		NADB_Rossmann	<212..286	CDD:304358
		Adk	363..583	CDD:223637	37/220 (17%)
		ADK	363..556	CDD:238713	33/196 (17%)
		Dpy-30	656..697	CDD:253069
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900