DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dak1 and cmpk

DIOPT Version :9

Sequence 1:	NP_651456.1	Gene:	Dak1 / 43165	FlyBaseID:	FBgn0028833	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_998274.2	Gene:	cmpk / 406383	ZFINID:	ZDB-GENE-040426-2113	Length:	219	Species:	Danio rerio

Alignment Length:	200	Identity:	121/200 - (60%)
Similarity:	153/200 - (76%)	Gaps:	8/200 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 HNIGIMSVEKPKIVFVLGGPGAGKGTQCSRIVDRFQFTHLSAGDLLREERSREGSEFGNLIEDYI 117
            |.:.:  :.||::|||||||||||||||:|||:.:.:|||||||||||||||..||||.||:.||
Zfish    18 HRLRV--IMKPQVVFVLGGPGAGKGTQCARIVENYSYTHLSAGDLLREERSRTDSEFGQLIDSYI 80

  Fly   118 RNGKIVPVEVTCSLLENAMKASGKS-----RFLIDGFPRNQDNLDGWNRQMSEKVDFQFVLFFDC 177
            :.||||||::|.:||..||:.:.|:     ||||||||||||||.|||.:|..|.|.:|||||||
Zfish    81 KEGKIVPVQITINLLRKAMEETMKADEKKFRFLIDGFPRNQDNLQGWNTEMDGKADVKFVLFFDC 145

  Fly   178 GEDVCVKRCLGRGQSGSGRTDDNLDSLKKRISTYNNDSLPIIKFFEGAGQVKRIDASPDAEEVFG 242
            ..:||:.|||.||:| |||||||.:||:|||.||...:.|||:.:|..|:|:|||||...:|||.
Zfish   146 SNEVCIDRCLERGKS-SGRTDDNRESLEKRIQTYLQSTRPIIELYEKQGKVQRIDASRSVDEVFA 209

  Fly   243 EVEKI 247
            :|:.|
Zfish   210 DVKNI 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dak1	NP_651456.1	UMP_CMP_kin_fam	65..249	CDD:273576	117/187 (63%)
Dak1	NP_651456.1	ADK	65..240	CDD:238713	113/179 (63%)
cmpk	NP_998274.2	UMP_CMP_kin_fam	28..215	CDD:273576	117/187 (63%)
cmpk	NP_998274.2	ADK	28..207	CDD:238713	113/179 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593090
Domainoid	1	1.000	213	1.000	Domainoid score	I2712
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32308
Inparanoid	1	1.050	244	1.000	Inparanoid score	I3274
OMA	1	1.010	-	-		QHG54223
OrthoDB	1	1.010	-	-		D1378291at2759
OrthoFinder	1	1.000	-	-		FOG0002780
OrthoInspector	1	1.000	-	-		oto39539
orthoMCL	1	0.900	-	-		OOG6_100591
Panther	1	1.100	-	-	LDO	PTHR23359
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1604
SonicParanoid	1	1.000	-	-		X1636
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.900