DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dak1 and CG9541

DIOPT Version :9

Sequence 1:	NP_651456.1	Gene:	Dak1 / 43165	FlyBaseID:	FBgn0028833	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001260273.1	Gene:	CG9541 / 34220	FlyBaseID:	FBgn0032083	Length:	646	Species:	Drosophila melanogaster

Alignment Length:	225	Identity:	52/225 - (23%)
Similarity:	106/225 - (47%)	Gaps:	35/225 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 ITTTSTAPPHNIGIMSVEKPK----------------IVFVLGGPGAGKGTQCSRIVD-RFQFTH 91
            :.|.:|:...:.|::..::||                |::|:||||:.|.|.|.:.|. ...:.|
  Fly   322 LKTGTTSADDDSGVVVTQQPKLRQAAGPDESGSDLPPIIWVIGGPGSNKATLCLKAVGLNPGWAH 386

  Fly    92 LSAGDLLR---EERSREGSEFGNLIEDYIRNGKIVPVEVTCSLLE-NAMKASGKSRFLIDGFPRN 152
            :|.|.|||   :...|..:| ...:::.:..|.:.|.:....||| |..:...::..::||:|||
  Fly   387 ISVGRLLRNITDSAPRANTE-SFAVKEALAAGDMAPEKSLNQLLETNLRQLRDRTGIIVDGYPRN 450

  Fly   153 QDNLDGWNRQMSEKVDFQFVLFFDCGEDVCVKRCLGRGQSGSGRTDDNLDSLKKRISTYNNDSLP 217
            ...:..:..:..::..   ::..||          .:.|.|.||.||.:.|.::|:..:...:||
  Fly   451 LQQVKYFENKYKQRPP---IILLDC----------SKLQLGRGRIDDTVSSFRRRLELFREQTLP 502

  Fly   218 IIKFFEGAGQVKRIDASPDAEEVFGEVEKI 247
            ::|..:.:.:::.:|...|:..|..|.|::
  Fly   503 MLKILDTSNRLQIVDGDTDSPSVQREFERL 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dak1	NP_651456.1	UMP_CMP_kin_fam	65..249	CDD:273576	47/188 (25%)
Dak1	NP_651456.1	ADK	65..240	CDD:238713	44/179 (25%)
CG9541	NP_001260273.1	aden_kin_iso1	67..238	CDD:130427
		ADK	70..230	CDD:238713
		aden_kin_iso1	358..521	CDD:130427	43/176 (24%)
		ADK	359..521	CDD:238713	43/175 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451277
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S511
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1378291at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23359
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.800