Protein Alignment Cmpk and AK2

DIOPT Version :10

• Sequence 1: NP_651456.1
• Gene: Cmpk / 43165
• FlyBaseID: FBgn0028833
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_001616.1
• Gene: AK2 / 204
• HGNCID: 362
• Length: 239
• Species: Homo sapiens
• Alignment Length: 228
• Identity: 69/228 - (30%)
• Similarity: 106/228 - (46%)
• Gaps: 40/228 - (17%)

  Fly    51 PPHNIGIMSVEKPKIVFVLGGPGAGKGTQCSRIVDRFQFTHLSAGDLLREERSREGSEFGNLIED 115
            |.:..||.:|       :||.||||||||..|:.:.|...||:.||:|| .....|||.|..::.
Human    10 PEYPKGIRAV-------LLGPPGAGKGTQAPRLAENFCVCHLATGDMLR-AMVASGSELGKKLKA 66

  Fly   116 YIRNGKIVPVEVTCSLLENAMKAS-GKSRFLIDGFP---RNQDNLDGWNRQMSEKVDFQFVLFFD 176
            .:..||:|..|:...|:|..::.. .|:.||:||||   |..:.||....:..||:|  .|:.|.
Human    67 TMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLD--SVIEFS 129

  Fly   177 CGEDVCVKRCLGR--------------------------GQSGSGRTDDNLDSLKKRISTYNNDS 215
            ..:.:.::|..||                          |:....|:|||..:||.|:..|:..:
Human   130 IPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQT 194

  Fly   216 LPIIKFFEGAGQVKRIDASPDAEEVFGEVEKIF 248
            .|:|:::...|....||||...:.||..:...|
Human   195 TPLIEYYRKRGIHSAIDASQTPDVVFASILAAF 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cmpk	NP_651456.1	UMP_CMP_kin_fam	65..249	CDD:273576	65/214 (30%)
AK2	NP_001616.1	Adk	17..226	CDD:440329	65/218 (30%)
		NMP. /evidence=ECO:0000255|HAMAP-Rule:MF_03168, ECO:0000269|Ref.17	45..74		10/29 (34%)
		LID. /evidence=ECO:0000255|HAMAP-Rule:MF_03168, ECO:0000269|Ref.17	141..178		4/36 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	150..169		0/18 (0%)