DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dak1 and F40F8.1

DIOPT Version :9

Sequence 1:	NP_651456.1	Gene:	Dak1 / 43165	FlyBaseID:	FBgn0028833	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001300543.1	Gene:	F40F8.1 / 174701	WormBaseID:	WBGene00009575	Length:	228	Species:	Caenorhabditis elegans

Alignment Length:	226	Identity:	119/226 - (52%)
Similarity:	153/226 - (67%)	Gaps:	5/226 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 ALTQHQLRHSKASNRFITTTSTAPPHNIGIMS-VEKPKIVFVLGGPGAGKGTQCSRIVDRFQFTH 91
            |...|.|..|.......|..||....:.|.:: .:...:|||||.||:||||.|::|.:...:.|
Worm     3 AFALHALIRSSHRLSLSTLHSTRQSVSFGTLTRNDMHNVVFVLGPPGSGKGTICAKIQENLNYVH 67

  Fly    92 LSAGDLLREERSREGSEFGNLIEDYIRNGKIVPVEVTCSLLENAMKASGKSR-FLIDGFPRNQDN 155
            ||||||||.||.|||||||.|||.:|:||.|||||:|||||||||||.|.:: ||:||||||:||
Worm    68 LSAGDLLRAERQREGSEFGALIESHIKNGSIVPVEITCSLLENAMKACGDAKGFLVDGFPRNEDN 132

  Fly   156 LDGWNRQMSEKVDFQFVLFFDCGEDVCVKRCLGRGQSGSGRTDDNLDSLKKRISTYNNDSLPIIK 220
            |.|||:||..|...|||||..|...:|::|||.|||   ||||||.:|||||:.|||..:.|||:
Worm   133 LQGWNKQMDGKALVQFVLFLSCPVSICIERCLNRGQ---GRTDDNEESLKKRVETYNQQTFPIIE 194

  Fly   221 FFEGAGQVKRIDASPDAEEVFGEVEKIFVAS 251
            .||.:|.|:.:.:....:.|:.:|||:|.|:
Worm   195 HFEKSGLVREVKSERPVDVVYADVEKVFDAA 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dak1	NP_651456.1	UMP_CMP_kin_fam	65..249	CDD:273576	109/184 (59%)
Dak1	NP_651456.1	ADK	65..240	CDD:238713	105/175 (60%)
F40F8.1	NP_001300543.1	UMP_CMP_kin_fam	41..223	CDD:273576	109/184 (59%)
F40F8.1	NP_001300543.1	ADK	41..214	CDD:238713	105/175 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165429
Domainoid	1	1.000	210	1.000	Domainoid score	I1640
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32308
Inparanoid	1	1.050	232	1.000	Inparanoid score	I2173
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54223
OrthoDB	1	1.010	-	-		D1378291at2759
OrthoFinder	1	1.000	-	-		FOG0002780
OrthoInspector	1	1.000	-	-		otm14142
orthoMCL	1	0.900	-	-		OOG6_100591
Panther	1	1.100	-	-	LDO	PTHR23359
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1604
SonicParanoid	1	1.000	-	-		X1636
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.840