DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dak1 and ak5

DIOPT Version :9

Sequence 1:	NP_651456.1	Gene:	Dak1 / 43165	FlyBaseID:	FBgn0028833	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_012815974.2	Gene:	ak5 / 100127649	XenbaseID:	XB-GENE-5764752	Length:	560	Species:	Xenopus tropicalis

Alignment Length:	213	Identity:	63/213 - (29%)
Similarity:	110/213 - (51%)	Gaps:	34/213 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 PHNIGIMSVEKPKIVFVLGGPGAGKGTQCSRIVDRFQFTHLSAGDLLREE-RSREGSEFGNLIED 115
            ||         |||:.|:||||:|||||..:|.:|:.|.::|.|:|||:: .|...:...:||..
Frog   130 PH---------PKIILVIGGPGSGKGTQSLKIAERYGFEYISVGELLRKKIHSTSSNRKWSLIAK 185

  Fly   116 YIRNGKIVPVEVTCS-LLENAMKASGKSRFLIDGFPRNQDNLDGWNRQMSEKVDFQ-------FV 172
            .|..|::.|.|.|.: :.:..|:.......:||||||:          :::.:.|:       .|
Frog   186 IITTGELAPQETTITEIKQKLMQIPDSEGIVIDGFPRD----------VAQALSFEDQICTPDLV 240

  Fly   173 LFFDCGEDVCVKRCLGRGQSGSGRTDDNLDSLKKRISTYNNDSLPIIKFFEGAGQVKRIDASPDA 237
            :|..|......:|...|.:. .||.||||.::::|:..:..:::|::.:|:..|.:...||..:.
Frog   241 VFLACASHKLKERLQKRAEQ-QGRPDDNLKAIQRRLMNFKQNAVPLVNYFQEKGLIITFDADREE 304

  Fly   238 EEVFGEV-----EKIFVA 250
            ||||.::     .|:|.|
Frog   305 EEVFCDISAAVDNKLFPA 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dak1	NP_651456.1	UMP_CMP_kin_fam	65..249	CDD:273576	57/197 (29%)
Dak1	NP_651456.1	ADK	65..240	CDD:238713	53/183 (29%)
ak5	XP_012815974.2	ADK	134..307	CDD:238713	53/183 (29%)
ak5	XP_012815974.2	aden_kin_iso1	372..559	CDD:130427
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1378291at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010