Protein Alignment Vps2 and Chmp2a

DIOPT Version :9

• Sequence 1: NP_651455.1
• Gene: Vps2 / 43164
• FlyBaseID: FBgn0039402
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_001347659.1
• Gene: Chmp2a / 68953
• MGIID: 1916203
• Length: 222
• Species: Mus musculus
• Alignment Length: 256
• Identity: 167/256 - (65%)
• Similarity: 199/256 - (77%)
• Gaps: 34/256 - (13%)

  Fly     1 MDWLFGKKISPDEMLRKNQRALNKAMRDLDRERMKMEQQEKKIIADIKKMAKEGQMDAVKIMAKD 65
            ||.|||::.:|:|:||:||||||:|||:|||||.|:|.||||||||||||||:||||||:|||||
Mouse     1 MDLLFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKD 65

  Fly    66 LVRTRRYAKKFMLMKANIQAVSLKIQTLKSQNTMAQAMKGVTKAMQNMNRQLNLPQIQKILQDFE 130
            |||||||.:||:||:|||||||||||||||.|:||||||||||||..|||||.|||||||:.:||
Mouse    66 LVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFE 130

  Fly   131 KQSEMMDMKEEMINDAIDDAMEDEGDEEETDAVVSQVLDELGLQLGEQLGDLPSASGSLSIAGGA 195
            :|:|:|||||||:||||||||.||.||||:|||||||||||||.|.::|.:|||..||||:|  |
Mouse   131 RQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLPSTGGSLSVA--A 193

  Fly   196 GAQKAQAVAAGGVGGGGAAGGGGASGGGAGGPGAPGGSGASSPMSDADADLQARLDKLRKD 256
            |.:||:|.|                                |.::||||||:.||..||:|
Mouse   194 GGKKAEATA--------------------------------SALADADADLEERLKNLRRD 222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps2	NP_651455.1	Snf7	17..185	CDD:281366	134/167 (80%)
Chmp2a	NP_001347659.1	Snf7	17..185	CDD:397437	134/167 (80%)
		Interaction with VPS4B. /evidence=ECO:0000250	56..222		125/199 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	179..198		11/20 (55%)
		MIT-interacting motif	210..220		5/9 (56%)
		Interaction with VTA1. /evidence=ECO:0000250	217..222		2/4 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830717
Domainoid	1	1.000	266	1.000	Domainoid score	I1881
eggNOG	1	0.900	-	-		E1_COG5491
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6382
Inparanoid	1	1.050	309	1.000	Inparanoid score	I2583
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53529
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005101
OrthoInspector	1	1.000	-	-		oto94113
orthoMCL	1	0.900	-	-		OOG6_102450
Panther	1	1.100	-	-	LDO	PTHR10476
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R316
SonicParanoid	1	1.000	-	-		X3622
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.790