DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gro and NSA1

DIOPT Version :9

Sequence 1:	NP_996298.1	Gene:	gro / 43162	FlyBaseID:	FBgn0001139	Length:	730	Species:	Drosophila melanogaster
Sequence 2:	NP_011404.1	Gene:	NSA1 / 852767	SGDID:	S000003079	Length:	463	Species:	Saccharomyces cerevisiae

Alignment Length:	173	Identity:	39/173 - (22%)
Similarity:	65/173 - (37%)	Gaps:	50/173 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   453 SNPTKYVYTGGKGCVKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLPDGRTLIVGGEASNLSIW 517
            |:.|||             .:|.|.| |.:|:|            |||:...|      |.:.::
Yeast   277 SHLTKY-------------STQHGRK-PFAQID------------LLPNREPL------SQMEVF 309

  Fly   518 D-----LASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTD 577
            |     :.|.....::|..:...     .|:.|.|        .|:..:|.:..:|.:..:....
Yeast   310 DAKGENVVSSLGNFQSETFNELN-----VITTDYK--------KNVFKFDGNGRMLGKVGRDDIT 361

  Fly   578 GASCIDISPDGSRLWTGGLDNTVRSWDLREGRQLQQHDFSSQI 620
            |:|......||..|..||||..||.:|::..:.|.:....|:|
Yeast   362 GSSTYIHVHDGKYLLQGGLDRYVRIFDIKTNKMLVKVYVGSRI 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gro	NP_996298.1	TLE_N	11..124	CDD:397828
		WD40	442..727	CDD:238121	39/173 (23%)
		WD40 repeat	447..486	CDD:293791	9/32 (28%)
		WD40 repeat	494..532	CDD:293791	8/42 (19%)
		WD40 repeat	537..573	CDD:293791	6/35 (17%)
		WD40 repeat	580..615	CDD:293791	12/34 (35%)
		WD40 repeat	620..653	CDD:293791	1/1 (100%)
		WD40 repeat	661..695	CDD:293791
		WD40 repeat	702..726	CDD:293791
NSA1	NP_011404.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910