DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment gro and SMU1

DIOPT Version :9

Sequence 1:	NP_996298.1	Gene:	gro / 43162	FlyBaseID:	FBgn0001139	Length:	730	Species:	Drosophila melanogaster
Sequence 2:	NP_177513.2	Gene:	SMU1 / 843707	AraportID:	AT1G73720	Length:	511	Species:	Arabidopsis thaliana

Alignment Length:	320	Identity:	66/320 - (20%)
Similarity:	112/320 - (35%)	Gaps:	86/320 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   446 VVCAVTISNPTKYVYTGGKGCVKVWDISQPGNKNPVSQLDCLQ---------------------- 488
            |...||:..|::.:...|:..  .|...| |...|.:|.|..:
plant   148 VAAEVTVVPPSRLMALIGQAL--KWQQHQ-GLLPPGTQFDLFRGTAAMKQDVEDTHPNVLTHTIK 209

  Fly   489 --RDNYIRSVKLLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISP------- 544
              :.::....:..|||:.|........:.:||..|  .::|.:|...|...:.:...|
plant   210 FGKKSHAECARFSPDGQFLASSSVDGFIEVWDYIS--GKLKKDLQYQADESFMMHDDPVLCIDFS 272

  Fly   545 -DSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVRSWDLREG 608
             ||::..|...||.|.:|.:...:.:|:|..|:.|.:.:..|.|||:|.:...|.|.|...|:.|
plant   273 RDSEMLASGSQDGKIKIWRIRTGVCIRRFDAHSQGVTSLSFSRDGSQLLSTSFDQTARIHGLKSG 337

  Fly   609 RQLQQ--------------HDFSSQIFSLGYCPTGDWLAVGMENSHVEVLHASKPDKYQLHLHES 659
            :.|::              .|.|..|.:...|....|     ::...:.|...||..
plant   338 KLLKEFRGHTSYVNHAIFTSDGSRIITASSDCTVKVW-----DSKTTDCLQTFKPPP-------- 389

  Fly   660 CVLSLRFAACGKWFVSTGKDNLLNAWRTPYGASIFQSKETSSVLSCDISTDDKYIVTGSG 719
               .||           |.|..:|:      ..:| .|.|..::.|: .|...||:|..|
plant   390 ---PLR-----------GTDASVNS------IHLF-PKNTEHIVVCN-KTSSIYIMTLQG 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gro	NP_996298.1	TLE_N	11..124	CDD:397828
		WD40	442..727	CDD:238121	66/320 (21%)
		WD40 repeat	447..486	CDD:293791	9/38 (24%)
		WD40 repeat	494..532	CDD:293791	9/37 (24%)
		WD40 repeat	537..573	CDD:293791	9/43 (21%)
		WD40 repeat	580..615	CDD:293791	11/48 (23%)
		WD40 repeat	620..653	CDD:293791	6/32 (19%)
		WD40 repeat	661..695	CDD:293791	5/33 (15%)
		WD40 repeat	702..726	CDD:293791	6/18 (33%)
SMU1	NP_177513.2	LisH_TPL	7..36	CDD:375350
		CTLH	40..91	CDD:128914
		WD40	204..510	CDD:238121	55/261 (21%)
		WD40 repeat	218..261	CDD:293791	10/44 (23%)
		WD40 repeat	267..303	CDD:293791	9/35 (26%)
		WD40 repeat	308..344	CDD:293791	11/35 (31%)
		WD40 repeat	351..386	CDD:293791	6/39 (15%)
		WD40 repeat	398..435	CDD:293791	10/38 (26%)
		WD40 repeat	443..478	CDD:293791
		WD40 repeat	485..509	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910