DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gro and DWA3

DIOPT Version :9

Sequence 1:	NP_996298.1	Gene:	gro / 43162	FlyBaseID:	FBgn0001139	Length:	730	Species:	Drosophila melanogaster
Sequence 2:	NP_176316.4	Gene:	DWA3 / 842414	AraportID:	AT1G61210	Length:	1181	Species:	Arabidopsis thaliana

Alignment Length:	333	Identity:	83/333 - (24%)
Similarity:	137/333 - (41%)	Gaps:	65/333 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   434 HARQINTLSHGEVVCAVTISNPTKYVYTGGKGC-VKVWDISQPGNKNPVSQLDCLQRDNYIRSVK 497
            |:..:|.||.|:        ..::...|||... |.:|.|.:     |.|.:......:.:.||
plant    14 HSANVNCLSIGK--------KTSRLFITGGDDYKVNLWAIGK-----PTSLMSLCGHTSAVDSV- 64

  Fly   498 LLPDGRTLIVGGEASN-LSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVW 561
            .......|::.|.:|. :.:||:..  .::....|.....|.|:...|..:...|..||.|:.:|
plant    65 AFDSAEVLVLAGASSGVIKLWDVEE--AKMVRAFTGHRSNCSAVEFHPFGEFLASGSSDANLKIW 127

  Fly   562 DLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVRSWDLREGRQLQQHDF-SSQIFSLGY 625
            |:..:..::.::||:.|.|.|..:|||..:.:|||||.|:.|||..|:.|.:..| ...|.||.:
plant   128 DIRKKGCIQTYKGHSRGISTIRFTPDGRWVVSGGLDNVVKVWDLTAGKLLHEFKFHEGPIRSLDF 192

  Fly   626 CPTGDWLAVGMENSHV--------EVLHASKPDKYQLHLHESCVLSLRF------AACG------ 670
            .|....||.|..:..|        |::.:::|:       .:.|.|::|      ..||
plant   193 HPLEFLLATGSADRTVKFWDLETFELIGSTRPE-------ATGVRSIKFHPDGRTLFCGLDDSLK 250

  Fly   671 --KWFVSTGKDNLLNAWRTPYGASIFQSKETSSVLSC------------DISTDDKYIVTGSGDK 721
              .|......|.:...|.|.....|.:.|    :|.|            |||..:.|.: ||.||
plant   251 VYSWEPVVCHDGVDMGWSTLGDLCISEGK----LLGCSYYQNSVGIWVSDISQIEPYGI-GSADK 310

  Fly   722 KATVYEVI 729
            |..|.:::
plant   311 KECVEKIL 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gro	NP_996298.1	TLE_N	11..124	CDD:397828
		WD40	442..727	CDD:238121	80/321 (25%)
		WD40 repeat	447..486	CDD:293791	8/39 (21%)
		WD40 repeat	494..532	CDD:293791	7/38 (18%)
		WD40 repeat	537..573	CDD:293791	9/35 (26%)
		WD40 repeat	580..615	CDD:293791	16/34 (47%)
		WD40 repeat	620..653	CDD:293791	10/40 (25%)
		WD40 repeat	661..695	CDD:293791	10/47 (21%)
		WD40 repeat	702..726	CDD:293791	11/35 (31%)
DWA3	NP_176316.4	WD40	8..260	CDD:238121	66/268 (25%)
		WD40 repeat	19..56	CDD:293791	12/49 (24%)
		WD40 repeat	61..97	CDD:293791	7/38 (18%)
		WD40 repeat	104..139	CDD:293791	8/34 (24%)
		WD40 repeat	145..181	CDD:293791	16/35 (46%)
		WD40 repeat	187..222	CDD:293791	9/34 (26%)
		WD40 repeat	229..252	CDD:293791	5/22 (23%)
		Herpes_BLLF1	<670..>908	CDD:282904
		Katanin_con80	1024..1175	CDD:404758
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910