DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment gro and SPA2

DIOPT Version :9

Sequence 1:	NP_996298.1	Gene:	gro / 43162	FlyBaseID:	FBgn0001139	Length:	730	Species:	Drosophila melanogaster
Sequence 2:	NP_192849.4	Gene:	SPA2 / 826712	AraportID:	AT4G11110	Length:	1036	Species:	Arabidopsis thaliana

Alignment Length:	714	Identity:	138/714 - (19%)
Similarity:	225/714 - (31%)	Gaps:	261/714 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 EEFNFLQAQYHSIKLECEKLS-NEKTEMQRHYVMYYEMSYGLNVEMHKQTEIAKRLNTLINQLLP 96
            :||:|..:|.|...:.|...| :|:.|.:     :|.....|..:|...:.....|..|:.:||.
plant   433 QEFHFRSSQPHCSTVACPFTSVSEQLEEK-----WYASPEELRGDMRSASSNIYSLGILLYELLS 492

  Fly    97 FLQADHQQQVLQAVERAKQVTMQELNLIIGHQQQHGIQQLLQQIHAQQVPGGPPQPMGALNPFGA 161
            ..|.          |||::..|.::        :|.|.              ||:.:.. ||..|
plant   493 QFQC----------ERAREAAMSDI--------RHRIL--------------PPKFLSE-NPKEA 524

  Fly   162 LGATMGLPHGPQGLLNKPPEHHRPDIKPTGLEGPAAAEERLRNSVSPADREKYRTRSPLDIENDS 226
             |..:.|.|        |....||           :..:.|::.|.....:.|.....|.||
plant   525 -GFCLWLLH--------PESSCRP-----------STRDILQSEVVNGIPDLYAEGLSLSIE--- 566

  Fly   227 KRRKDEKLQEDEGEKSDQDLVVDVANEMESHSPRPNGEHVSMEVRDRESLNGERLEKPSSSGIKQ 291
                    |||...:..|..:.....:.:.|:.....|..|:|. |.|    |.:::..:.|
plant   567 --------QEDTESELLQHFLFLSQEKRQKHAGNLMEEIASVEA-DIE----EIVKRRCAIG--- 615

  Fly   292 ERPPSRSGSSSSRSTPSLKTKDMEKPGTPGAKARTPTPNAAAPAPGV--NPKQMMPQGPPPAGYP 354
              |||...:|||                        :|.::.|...:  |..|:
plant   616 --PPSLEEASSS------------------------SPASSVPEMRLIRNINQL----------- 643

  Fly   355 GAPYQRPADPYQRPPSDPAYGRPPPMPYDPHAHVRTNGIPHPSALTGGKPAYSFHMNGEGSLQPV 419
                            :.||.......:.|.|..|.            :|......|.:.::..|
plant   644 ----------------ESAYFAARIDAHLPEARYRL------------RPDRDLLRNSDNTVAEV 680

  Fly   420 ----PFPPDALVGV---GIPRHAR-------------QINTLSHGEVVCAVTISNPTKYVYTGG- 463
                .:..|..||.   |:.::||             ::|..|:  |:|::.......|..|.|
plant   681 ENSETWSSDDRVGAFFDGLCKYARYSKFETRGVLRTSELNNTSN--VICSLGFDRDEDYFATAGV 743

  Fly   464 KGCVKVW----------DISQPGNKNP-VSQLDCLQRDNYIRS----------VKLLPDGRTLIV 507
            ...:|::          ||..|..:.| .|:|..:..:||||:          |||..     :.
plant   744 SKKIKIYEFNSLFNESVDIHYPAIEMPNRSKLSGVCWNNYIRNYLASSDYDGIVKLWD-----VT 803

  Fly   508 GGEASNLSI------WDL----ASPTPRIKAELTSAAPACYALAISPDSKVCFS--------CC- 553
            .|:|.:..|      |.:    |.||     :|.|.:..|.....:.:.:.|..        ||
plant   804 TGQAISHFIEHEKRAWSVDFSEACPT-----KLASGSDDCSVKLWNINERNCLGTIRNIANVCCV 863

  Fly   554 --------------SDGNIAVWDLHNEILVRQ----FQGHTDGASCIDISPDGSRLWTGGLDNTV 600
                          ||.....:||.|   :|.    ..||....|..... |...|.|...|||:
plant   864 QFSPQSSHLLAFGSSDFRTYCYDLRN---LRTPWCILSGHNKAVSYAKFL-DNETLVTASTDNTL 924

  Fly   601 RSWDLRE---------------GRQLQQHDFSSQIFSLGYCPTGDWLAVGMENSHVEVLHASKP 649
            :.|||::               |....:.:|      :|...:..::|.|.|.:.|...|.|.|
plant   925 KLWDLKKTTHGGLSTNACSLTFGGHTNEKNF------VGLSTSDGYIACGSETNEVYAYHRSLP 982

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gro	NP_996298.1	TLE_N	11..124	CDD:397828	21/91 (23%)
		WD40	442..727	CDD:238121	61/282 (22%)
		WD40 repeat	447..486	CDD:293791	11/50 (22%)
		WD40 repeat	494..532	CDD:293791	12/57 (21%)
		WD40 repeat	537..573	CDD:293791	10/62 (16%)
		WD40 repeat	580..615	CDD:293791	11/49 (22%)
		WD40 repeat	620..653	CDD:293791	8/30 (27%)
		WD40 repeat	661..695	CDD:293791
		WD40 repeat	702..726	CDD:293791
SPA2	NP_192849.4	PLN00181	299..1036	CDD:177776	138/714 (19%)
		PKc_like	<299..548	CDD:304357	35/172 (20%)
		WD40	723..1032	CDD:238121	61/282 (22%)
		WD40 repeat	726..769	CDD:293791	8/42 (19%)
		WD40 repeat	776..813	CDD:293791	9/41 (22%)
		WD40 repeat	818..855	CDD:293791	8/41 (20%)
		WD40 repeat	861..897	CDD:293791	8/38 (21%)
		WD40 repeat	904..947	CDD:293791	10/43 (23%)
		WD40 repeat	954..1002	CDD:293791	9/35 (26%)
		WD40 repeat	1009..1032	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910