Protein Alignment gro and gnb5a

DIOPT Version :9

• Sequence 1: NP_996298.1
• Gene: gro / 43162
• FlyBaseID: FBgn0001139
• Length: 730
• Species: Drosophila melanogaster
• Sequence 2: NP_001073650.1
• Gene: gnb5a / 562813
• ZFINID: ZDB-GENE-070112-342
• Length: 355
• Species: Danio rerio
• Alignment Length: 303
• Identity: 76/303 - (25%)
• Similarity: 129/303 - (42%)
• Gaps: 31/303 - (10%)

  Fly   443 HG-EVVCAVTISNPTKYVYTGGKGCVKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLPDGRTLI 506
            || :|:|.....:..:.|.:...|.|.||| :...||.....:.|    .::.:....|.|..:.
Zfish    64 HGNKVLCMDWCKDKRRIVSSSQDGKVIVWD-AFTTNKEHAVTMPC----TWVMACAYAPSGCAVA 123

  Fly   507 VGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCF--------SCCSDGNIAVWDL 563
            .||..:..|::.|:..    |.|..:|.....|:..:..|..||        :...||..|:||:
Zfish   124 CGGLDNKCSVYPLSLD----KNENLAAKKKSVAMHTNYLSACCFTNSDMQILTSSGDGTCALWDV 184

  Fly   564 HNEILVRQFQGHTDGASCIDISPD--GSRLWTGGLDNTVRSWDLREGRQLQ---QHDFSSQIFSL 623
            .:..:::.|.||.....|:|::|.  |:...:||.|.....||:|.|:.:|   .||  |.|.|:
Zfish   185 ESGQMLQSFHGHAADVLCLDLAPSETGNTFVSGGCDKKACVWDMRTGQCVQSFESHD--SDINSV 247

  Fly   624 GYCPTGDWLAVGMENSHVEVLHASKPDKYQLHLHESCVL---SLRFAACGKWFVSTGKDNLLNAW 685
            .|.|:||..|.|.:::...:.......:..::..||.:.   |:.|:..|:.......|..:|.|
Zfish   248 RYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFGGYNDYTINVW 312

  Fly   686 RTPYGA--SIFQSKETSSVLSCDISTDDKYIVTGSGDKKATVY 726
            ....||  ||....| :.|.:..:|.|.....:||.|....::
Zfish   313 DVLKGARVSILFGHE-NRVSTLRVSPDGTAFCSGSWDHTLRIW 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gro	NP_996298.1	TLE_N	11..124	CDD:397828
		WD40	442..727	CDD:238121	76/303 (25%)
		WD40 repeat	447..486	CDD:293791	9/38 (24%)
		WD40 repeat	494..532	CDD:293791	8/37 (22%)
		WD40 repeat	537..573	CDD:293791	9/43 (21%)
		WD40 repeat	580..615	CDD:293791	12/39 (31%)
		WD40 repeat	620..653	CDD:293791	8/32 (25%)
		WD40 repeat	661..695	CDD:293791	10/38 (26%)
		WD40 repeat	702..726	CDD:293791	6/23 (26%)
gnb5a	NP_001073650.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23
		WD40	58..355	CDD:238121	76/303 (25%)
		WD 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00221	63..102		12/38 (32%)
		WD40 repeat	68..105	CDD:293791	10/37 (27%)
		WD 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00221	105..144		9/46 (20%)
		WD40 repeat	111..153	CDD:293791	9/45 (20%)
		WD 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU00221	153..194		8/40 (20%)
		WD40 repeat	158..194	CDD:293791	8/35 (23%)
		WD 4. /evidence=ECO:0000255|PROSITE-ProRule:PRU00221	195..238		14/42 (33%)
		WD40 repeat	203..238	CDD:293791	11/34 (32%)
		WD 5. /evidence=ECO:0000255|PROSITE-ProRule:PRU00221	239..278		11/40 (28%)
		WD40 repeat	244..280	CDD:293791	8/35 (23%)
		WD 6. /evidence=ECO:0000255|PROSITE-ProRule:PRU00221	280..322		10/41 (24%)
		WD40 repeat	288..324	CDD:293791	10/35 (29%)
		WD 7. /evidence=ECO:0000255|PROSITE-ProRule:PRU00221	325..355		7/31 (23%)
		WD40 repeat	330..354	CDD:293791	6/23 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910