DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment gro and eif3i

DIOPT Version :9

Sequence 1:NP_996298.1 Gene:gro / 43162 FlyBaseID:FBgn0001139 Length:730 Species:Drosophila melanogaster
Sequence 2:NP_001015781.1 Gene:eif3i / 548498 XenbaseID:XB-GENE-974377 Length:325 Species:Xenopus tropicalis


Alignment Length:197 Identity:44/197 - (22%)
Similarity:82/197 - (41%) Gaps:15/197 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly   545 DSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVRSWDLREGR 609
            |..:.|:...|..:.||...|...:..:.|||....|:|:..|...:.:|..||:.|.||...|:
 Frog    21 DGDLLFTVAKDPVVNVWYSVNGERLGTYSGHTGAVWCVDVDWDTRHVLSGSADNSCRLWDCETGK 85

  Fly   610 QLQQHDFSSQIFSLGYCPTGDWLAVGMENS-----HVEVLHASKPDKYQ-------LHLHESCVL 662
            ||...:.:|.:.:.|:...|:.:....:..     .|..:....|.:.:       :...||.:.
 Frog    86 QLALLETNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFIDLRDPTQIEDNEPYMKIPCSESKIT 150

  Fly   663 SLRFAACGKWFVSTGKDNLLNAWRTPYGASIFQSKETSSVLSCDIST--DDKYIVTGSGDKKATV 725
            |..:...|:..::..::..||.:....|..:...||.|..:: ||.|  |....||.|.|..:.:
 Frog   151 SAVWGPLGENIIAGHENGELNQYSAKSGEIVNSIKEHSKQIN-DIQTSRDMTMFVTASKDCTSKL 214

  Fly   726 YE 727
            ::
 Frog   215 FD 216

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
groNP_996298.1 TLE_N 11..124 CDD:397828
WD40 442..727 CDD:238121 44/195 (23%)
WD40 repeat 447..486 CDD:293791
WD40 repeat 494..532 CDD:293791
WD40 repeat 537..573 CDD:293791 6/27 (22%)
WD40 repeat 580..615 CDD:293791 12/34 (35%)
WD40 repeat 620..653 CDD:293791 4/37 (11%)
WD40 repeat 661..695 CDD:293791 5/33 (15%)
WD40 repeat 702..726 CDD:293791 8/25 (32%)
eif3iNP_001015781.1 WD40 6..311 CDD:392136 44/197 (22%)
WD 1 8..47 6/25 (24%)
WD40 repeat 14..50 CDD:293791 6/28 (21%)
WD 2 50..89 15/38 (39%)
WD40 repeat 55..91 CDD:293791 12/35 (34%)
WD 3 144..183 7/38 (18%)
WD40 repeat 150..185 CDD:293791 5/34 (15%)
WD 4 186..225 10/32 (31%)
WD40 repeat 191..226 CDD:293791 8/27 (30%)
WD40 repeat 232..272 CDD:293791
WD 5 283..324
WD40 repeat 288..311 CDD:293791
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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